KIN-193
National Institutes of Health
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Objective Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide. Thus far, most drugs have failed…
Aberrant activation of the PI3K pathway is a common alteration in human cancers. Therapeutic intervention targeting the PI3K…
UNLABELLED
Genetic approaches have shown that the p110β isoform of class Ia phosphatidylinositol-3-kinase (PI3K) is essential for…
Although it has been known for some time that PTEN-null tumors require expression of the p110β isoform of phosphoinositide 3…