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KIAA1462 gene

Known as: JCAD, JUNCTIONAL PROTEIN ASSOCIATED WITH CORONARY ARTERY DISEASE, KIAA1462 
 
National Institutes of Health

Related topics

Related topics

1 relation
Chromosome 10 Short Arm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.
AIMS Recent genome-wide association studies (GWAS) have identified that the JCAD locus is associated with risk of coronary artery… Expand
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2017
2017
Targeted Disruption of JCAD (Junctional Protein Associated With Coronary Artery Disease)/KIAA1462, a Coronary Artery Disease–Associated Gene Product, Inhibits Angiogenic Processes In Vitro and In…
Objective— Recent genome-wide association studies newly identified the human KIAA1462 gene as a new locus for coronary artery… Expand
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2017
2017
Genome‐Wide Association Study of the Genetic Determinants of Emphysema Distribution
Rationale: Emphysema has considerable variability in the severity and distribution of parenchymal destruction throughout the… Expand
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2017
2017
JCAD Promotes Progression of Nonalcoholic Steatohepatitis to Liver Cancer by Inhibiting LATS2 Kinase Activity.
Nonalcoholic steatohepatitis-associated hepatocellular carcinoma (NASH-HCC) is a malignancy whose incidents are rapidly… Expand
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2013
2013
KIAA1462, A Coronary Artery Disease Associated Gene, Is a Candidate Gene for Late Onset Alzheimer Disease in APOE Carriers
Alzheimer disease (AD) is a devastating neurodegenerative disease affecting more than five million Americans. In this study, we… Expand
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Highly Cited
2011
Highly Cited
2011
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
Genome-wide association studies have identified 11 common variants convincingly associated with coronary artery disease (CAD), a… Expand
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2011
2011
A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions.
Cell-cell junctions play crucial roles in the organization and function of epithelial and endothelial cellular sheets. Here, we… Expand
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2011
2011
A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions
 
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Highly Cited
2009
Highly Cited
2009
Genetic Analysis of Variation in Human Meiotic Recombination
The number of recombination events per meiosis varies extensively among individuals. This recombination phenotype differs between… Expand
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2006
2006
A novel nuclear-encoded mitochondrial poly(A) polymerase PAPD1 is a potential candidate gene for the extreme obesity related phenotypes in mammals
People with obesity, especially extreme obesity, are at risk for many health problems. However, the responsible genes remain… Expand
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