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KERA gene

Known as: KERA, SLRR2B, keratocan proteoglycan 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
FGF-2- and TGF-β1-induced downregulation of lumican and keratocan in activated corneal keratocytes by JNK signaling pathway.
PURPOSE Downregulation of lumican and keratocan expression is an undesirable phenotypic change that occurs during corneal wound… 
Highly Cited
2008
Highly Cited
2008
Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control…
IntroductionThe small leucine-rich proteoglycans (SLRPs) modulate tissue organization, cellular proliferation, matrix adhesion… 
Highly Cited
2007
Highly Cited
2007
Keratocan and Lumican Regulate Neutrophil Infiltration and Corneal Clarity in Lipopolysaccharide-induced Keratitis by Direct Interaction with CXCL1*
Keratocan and lumican are keratan-sulfate proteoglycans (KSPG), which have a critical role in maintaining corneal clarity. To… 
2006
2006
Stimulation of collagen synthesis by insulin and proteoglycan accumulation by ascorbate in bovine keratocytes in vitro.
PURPOSE Ascorbate is required for the hydroxylation of collagen that is present in the corneal stroma. The keratan sulfate… 
Highly Cited
2003
Highly Cited
2003
Human keratocytes cultured on amniotic membrane stroma preserve morphology and express keratocan.
PURPOSE To develop a new method of expanding human corneal keratocytes in serum while maintaining their characteristic morphology… 
Highly Cited
2003
Highly Cited
2003
Keratocan-deficient Mice Display Alterations in Corneal Structure*
Keratocan (Kera) is a cornea-specific keratan sulfate proteoglycan (KSPG) in the adult vertebrate eye. It belongs to the small… 
2003
2003
An X-ray scattering investigation of corneal structure in keratocan-deficient mice.
Highly Cited
2000
Highly Cited
2000
Expression of the keratan sulfate proteoglycans lumican, keratocan and osteoglycin/mimecan during chick corneal development.
The corneal proteoglycans belong to the Leu-rich proteoglycan (LRP) gene family and contain chondroitin/dermatan (CS/DS) or… 
Highly Cited
2000
Highly Cited
2000
Super‐motifs and evolution of tandem leucine‐rich repeats within the small proteoglycans—biglycan, decorin, lumican, fibromodulin, PRELP, keratocan, osteoadherin, epiphycan, and osteoglycin
Leucine‐rich repeats (LRRs) with 20–30 amino acids in unit length are present in many proteins from prokaryotes to eukaryotes… 
Highly Cited
1996
Highly Cited
1996
Molecular Cloning and Tissue Distribution of Keratocan
Previous studies showed that the keratan sulfate-containing proteoglycans of bovine corneal stroma contain three unique core… 
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