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KEAP1 gene

Known as: MGC9454, kelch-like family member 19, Kelch-Like ECH-Associated Protein 1 Gene 
This gene is involved in ubiquitin-mediated protein degradation.
National Institutes of Health

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2 relations
KEAP1 protein, humanKelch-Like ECH-Associated Protein 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Inflammatory and Senescent Phenotype of Pancreatic Stellate Cells Induced by Sqstm1 Downregulation Facilitates Pancreatic Cancer Progression
Pancreatic ductal adenocarcinoma (PDAC) has unique microenvironment with extensive infiltration of fibroblasts, which are mainly… 
2019
2019
PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC
Chemotherapy resistance is a major problem in non-small cell lung cancer (NSCLC) treatment. A major mechanism of chemoresistance… 
2015
2015
Expression of LC3, LAMP2, KEAP1 and NRF2 in Salivary Adenoid Cystic Carcinoma
Salivary Adenoid Cystic Carcinoma (SACC) is a tumor characterized by inevitable local progression and terminal hematogenous… 
2013
2013
The S349T mutation of SQSTM1 links Keap1/Nrf2 signalling to Paget's disease of bone.
2013
2013
Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin
Clinical epidemiology has indicated that the endothelial injury is a potential contributor to the pathogenesis of ischemic… 
2012
2012
Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2–Cul3–Rbx1 complex to allow normal Nrf2 activation and repression
INrf2 (Keap1) serves as a negative regulator of the cytoprotective transcription factor Nrf2. At basal levels, INrf2 functions as… 
2010
2010
Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3-RINGBox1 protein complex and elucidation of its quaternary structure with Keap1.
2007
2007
Genetic variations and haplotype structures of transcriptional factor Nrf2 and its cytosolic reservoir protein Keap1 in Japanese.
Transcriptional factor Nrf2 and its cytosolic reservoir protein Keap1 play important roles in induction of the expression of… 
2004
2004
Fetal Alz-50 clone 1 interacts with the human orthologue of the Kelch-like Ech-associated protein.
The fetal Alz-50 reactive clone 1 (FAC1) protein exhibits altered expression and subcellular localization during neuronal… 
1998
1998
Effects of language experience on speech perception
Language experience during the first year of life has a dramatic effect on infants’ perception and production of speech. In this… 
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