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KCNQ1OT1 wt Allele

Known as: Non-Protein Coding RNA 12 Gene, NCRNA00012, KCNQ1 Opposite Strand/Antisense Transcript 1 (Non-Protein Coding) wt Allele 
Human KCNQ1OT1 wild-type allele is located in the vicinity of 11p15 and is approximately 92 kb in length. This allele, which encodes KCNQ1 opposite… 
National Institutes of Health

Related topics

Related topics

3 relations
11p15Epigenetic ProcessTranscriptional Regulation

Papers overview

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Highly Cited
2010
Highly Cited
2010
Quantitative methylation analysis of developmentally important genes in human pregnancy losses after ART and spontaneous conception.
To study possible effects of assisted reproductive technologies (ART) on epigenetic reprogramming, we have analyzed the DNA… 
Highly Cited
2009
Highly Cited
2009
Clone‐ and Gene‐Specific Aberrations of Parental Imprinting in Human Induced Pluripotent Stem Cells
Genomic imprinting is an epigenetic phenomenon whereby genes are expressed in a monoallelic manner, which is inherited either… 
Highly Cited
2009
Highly Cited
2009
Abnormal methylation at the KvDMR1 imprinting control region in clinically normal children conceived by assisted reproductive technologies.
Genomic imprinting alterations have been shown to be associated with assisted reproductive technologies (ARTs) in animals. At… 
Highly Cited
2008
Highly Cited
2008
Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development.
In vitro culture of mouse embryos results in loss of imprinting. The aim of the present study was to examine how two of the… 
Highly Cited
2008
Highly Cited
2008
Two distinct mechanisms of silencing by the KvDMR1 imprinting control region
Imprinting control regions (ICRs) are known to repress genes by utilizing one of two mechanisms, CTCF‐mediated insulation or the… 
Review
2008
Review
2008
Regulation of imprinting in clusters: noncoding RNAs versus insulators.
Highly Cited
2003
Highly Cited
2003
In vitro fertilization may increase the risk of Beckwith-Wiedemann syndrome related to the abnormal imprinting of the KCN1OT gene.
To the Editor: “Parental imprinting” refers to an epigenetic marking of genes that results in monoallelic expression. This… 
Highly Cited
2003
Highly Cited
2003
Silencing of CDKN1C (p57KIP2) is associated with hypomethylation at KvDMR1 in Beckwith–Wiedemann syndrome
Context: Beckwith–Wiedemann syndrome (BWS) arises by several genetic and epigenetic mechanisms affecting the balance of imprinted… 
Highly Cited
2002
Highly Cited
2002
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1
Genomic imprinting is an epigenetic modification that results in expression from only one of the two parental copies of a gene… 
Highly Cited
2001
Highly Cited
2001
Analysis of the methylation status of the KCNQ1OT and H19 genes in leukocyte DNA for the diagnosis and prognosis of Beckwith–Wiedemann syndrome
Beckwith–Wiedemann syndrome (BWS) is an overgrowth disorder involving developmental abnormalities, tissue and organ hyperplasia… 
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