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Two-pore-domain K+ (K2P) channels sense a wide variety of stimuli such as mechanical stress, inhalational anesthetics, and… Expand BACKGROUND
Arsenic is a well-documented carcinogen of human urothelial carcinoma (UC) with incompletely understood mechanisms… Expand Analyzing a patient with progressive and severe cardiac conduction disorder combined with idiopathic ventricular fibrillation… Expand K+ channels share common selectivity characteristics but exhibit a wide diversity in how they are gated open. Leak K2P K… Expand Hematopoietic stem cells (HSCs) are used therapeutically for hematological diseases and may also serve as a source for… Expand BACKGROUND
Genetic factors contribute to the development of ischemic stroke (IS). In order to identify susceptibility variants… Expand This study firstly shows with in situ hybridization on human pancreas that TALK‐1 and TALK‐2, two members of the 2P domain… Expand The two-pore K2P channel family comprises TASK, TREK, TWIK, TRESK, TALK, and THIK subfamilies, and TALK-1, TALK-2, and TASK-2 are… Expand We isolated three novel 2P domain K(+) channel subunits from human. The first two subunits, TALK-1 and TALK-2, are distantly… Expand We report the primary sequence of TASK‐4, a novel member of the acid‐sensitive subfamily of tandem pore K+ channels. TASK‐4… Expand