FAQ

KCNK1 gene

Known as: POTASSIUM CHANNEL, SUBFAMILY K, MEMBER 1, potassium two pore domain channel subfamily K member 1, K2P1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
02419972017

Related topics

Related topics

1 relation
KCNK10 gene

Related mentions per year

Related mentions per year

1997-2018
1990200020102020
KCNK1 gene
KCNK10 gene

Papers overview

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2014
2014
A disulphide-linked heterodimer of TWIK-1 and TREK-1 mediates passive conductance in astrocytes.
TWIK-1 is a member of the two-pore domain K(+) (K2P) channel family that plays an essential part in the regulation of resting… (More)
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2013
2013
The contribution of TWIK-1 channels to astrocyte K+ current is limited by retention in intracellular compartments
TWIK-1 two-pore domain K(+) channels are expressed abundantly in astrocytes. In the present study, we examined the extent to… (More)
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2013
2013
Expression of background potassium channels in rat DRG is cell-specific and down-regulated in a neuropathic pain model.
Neuropathic pain is associated with hyperexcitability of DRG neurons. Despite the importance of leakage potassium channels for… (More)
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2012
2012
Genome-wide association study of periodontal pathogen colonization.
Pathological shifts of the human microbiome are characteristic of many diseases, including chronic periodontitis. To date, there… (More)
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2011
2011
Changes in ion channel gene expression underlying heart failure-induced sinoatrial node dysfunction.
BACKGROUND Heart failure (HF) causes a decline in the function of the pacemaker of the heart-the sinoatrial node (SAN). The aim… (More)
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2007
2007
Does Sumoylation Control K2P1/TWIK1 Background K+ Channels?
A novel model for the regulation of cell excitability has recently been proposed. It originates from the observation that the… (More)
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Highly Cited
2007
Highly Cited
2007
Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway
To identify genes dysregulated in bipolar disorder (BD1), we carried out global gene expression profiling using whole-genome… (More)
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2004
2004
ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6.
TWIK1 belongs to a family of K(+) channels involved in neuronal excitability and cell volume regulation. Its tissue distribution… (More)
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1998
1998
Structure, chromosome localization, and tissue distribution of the mouse twik K+ channel gene.
We have recently discovered a new class of potassium channels with two pore-forming domains and four membrane-spanning domains… (More)
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1997
1997
Cloning and localization of a double-pore K channel, KCNK1: exclusive expression in distal nephron segments.
The K-selective channel, TOK1, recently identified in yeast, displays the unusual structural feature of having two putative pore… (More)
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