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KB 141
Known as:
KB-141
, KB141 cpd
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Phenyl Ethers
Phenylacetates
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Analysis of the roles of mutations in thyroid hormone receptor-β by a bacterial biosensor system.
Changhua Shi
,
Qing Meng
,
D. Wood
Journal of Molecular Endocrinology
2014
Corpus ID: 207143901
Mutations in thyroid hormone receptors (TRs) often lead to metabolic and developmental disorders, but patients with these…
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2012
2012
Bacterial biosensors for screening isoform-selective ligands for human thyroid receptors α-1 and β-1
Izabela Gierach
,
Jingjing Li
,
Wan-yi Wu
,
G. Grover
,
D. Wood
FEBS Open Bio
2012
Corpus ID: 2866725
Review
2008
Review
2008
Metabolic effects of thyroid hormone derivatives.
M. Moreno
,
P. de Lange
,
A. Lombardi
,
E. Silvestri
,
A. Lanni
,
F. Goglia
Thyroid
2008
Corpus ID: 13270685
The processes and pathways mediating the intermediary metabolism of carbohydrates, lipids, and proteins are all affected by…
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Highly Cited
2008
Highly Cited
2008
Anti-obesity, anti-diabetic, and lipid lowering effects of the thyroid receptor β subtype selective agonist KB-141
G. Bryzgalova
,
S. Effendic
,
+10 authors
G. Grover
Journal of Steroid Biochemistry and Molecular…
2008
Corpus ID: 23436878
2008
2008
Les analogues des hormones thyroïdiennes : un apport biologique important et de nouvelles possibilités thérapeutiques
C. Josseaume
,
Y. Lorcy
2008
Corpus ID: 82357352
Highly Cited
2007
Highly Cited
2007
Targeting thyroid hormone receptor-β agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index
M. Erion
,
E. Cable
,
+8 authors
D. Linemeyer
Proceedings of the National Academy of Sciences
2007
Corpus ID: 21880522
Despite efforts spanning four decades, the therapeutic potential of thyroid hormone receptor (TR) agonists as lipid-lowering and…
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Review
2007
Review
2007
Therapeutic potential for thyroid hormone receptor-beta selective agonists for treating obesity, hyperlipidemia and diabetes.
G. Grover
,
K. Mellström
,
J. Malm
Current Vascular Pharmacology
2007
Corpus ID: 28653358
Obesity and metabolic syndrome are increasing dramatically worldwide, contributing to cardiovascular morbidity and mortality…
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Review
2006
Review
2006
Development of the thyroid hormone receptor beta-subtype agonist KB-141: a strategy for body weight reduction and lipid lowering with minimal cardiac side effects.
G. Grover
,
K. Mellstrom
,
J. Malm
Cardiovascular Drug Reviews
2006
Corpus ID: 26073180
Few treatments for obesity exist and improvements for treatment of hyperlipidemia are still desirable. Thyroid hormone receptors…
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2006
2006
Thyroid receptor ligands. Part 4: 4'-amido bioisosteric ligands selective for the thyroid hormone receptor beta.
Yi-lin Li
,
C. Litten
,
+8 authors
J. Malm
Bioorganic & Medicinal Chemistry Letters
2006
Corpus ID: 21326794
Highly Cited
2003
Highly Cited
2003
Selective thyroid hormone receptor-β activation: A strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability
G. Grover
,
K. Mellström
,
+12 authors
J. Baxter
Proceedings of the National Academy of Sciences…
2003
Corpus ID: 24937322
Few treatments for obesity exist and, whereas efficacious therapeutics for hyperlipidemia are available, further improvements are…
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