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K-604

National Institutes of Health

Papers overview

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2016
2016
An ACAT-1Inhibitor, K-604, Ameliorates Hepatic Inflammation in NAFLD and NASH Models
A high level of cholesterol activates Kupffer cells, which subsequently triggers inflammation and ultimately leads to… 
2009
2009
A novel technical approach for the measurement of individual ACAT-1 and ACAT-2 enzymatic activity in the testis.
Acyl-coenzyme A:cholesterol acyltransferase (ACAT) is implicated in the esterification of cholesterol when the latter is present… 
2009
2009
Abstract: P292 A SELECTIVE ACAT1 INHIBITOR, K-604, STABILIZES ATHEROSCLEROTIC LESION VERSUS PACTIMIBE IN APOLIPOPROPTEIN E-KNOCKOUT MICE
2006
2006
Abstract 1197: A Selective ACAT1 Inhibitor, K-604, Stabilizes Atherosclerotic Lesion Versus Pactimibe in Apolipoprotein E-Knockout Mice
2006
2006
Th-P16:249 An ACAT1 selective inhibitor, K-604 directly regulates atherosclerotic lesions. A comparison study with the ACAT1/2 non-selective inhibitor CS-505
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