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Janus Kinase Inhibitors [MoA]

Known as: Janus Kinase Inhibitors 
National Institutes of Health

Papers overview

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2020
2020
Background and importance Tofacitinib and baricitinib are oral Janus kinase inhibitors (JKi) approved for the treatment of… 
2019
2019
Background The Janus kinase inhibitors (JAKi) peficitinib and filgotinib are currently examined in clinical trials for treatment… 
2019
2019
Background ACR guidelines recommend starting rheumatoid arthritis (RA) treatment with conventional-synthetic (cs)DMARD… 
2018
2018
Background Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus… 
2018
2018
Introduction In 2017, the Janus kinase inhibitors (JAKi) Tofacitinib and Baricitinib were approved for the treatment of… 
2016
2016
Background Baricitinib (bari) and tofacitinib (tofa) are selective JANUS kinase inhibitors (JAKi). In biochemical assays, bari… 
Review
2015
Review
2015
Hodgkin lymphoma (HL) is highly curable lymphoma with combined multiagent chemotherapy with or without radiation. In spite of…