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JTT 130

Known as: JTT-130, JTT130 
National Institutes of Health

Papers overview

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2015
2015
JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates lipid metabolism and attenuates atherosclerosis in hyperlipidemic animal models.
2014
2014
Combination Therapy of an Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein and Peroxisome Proliferator-Activated Receptor γ Agonist in Diabetic Rat
We investigated effects on glucose and lipid metabolism in combination of JTT-130, a novel intestine-specific microsomal… 
2012
2012
Insights into the novel hydrolytic mechanism of a diethyl 2-phenyl-2-(2-arylacetoxy)methyl malonate ester-based microsomal triglyceride transfer protein (MTP) inhibitor.
Inhibition of intestinal and hepatic microsomal triglyceride transfer protein (MTP) is a potential strategy for the treatment of… 
2006
2006
Drug evaluation: The MTP inhibitor JTT-130 as a potential treatment for hyperlipidemia.
  • J. Burnett
  • IDrugs : the investigational drugs journal
  • 2006
  • Corpus ID: 30052305
Japan Tobacco Inc is developing JTT-130, an orally active microsomal triglyceride transfer protein inhibitor, for the potential… 
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