JSM10292
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
GPCR are integral membrane receptor proteins that are characterized by heptahelical transmembrane domains connected by…
Bradykinin (BK) is a member of the kinin family, released in response to inflammation, trauma, burns, shock, allergy and some…
Abstract: Bradykinin (BK) is a member of the kinin family, released in response to inflammation, trauma, burns, shock, allergy…
BACKGROUND AND PURPOSE A 3H‐labelled derivative of the novel small‐molecule bradykinin (BK) B2 receptor antagonist JSM10292 was…
Upon activation the human bradykinin B2 receptor (B2R) acts as guanine nucleotide exchange factor for the G proteins Gq/11 and Gi…
Blockade of the bradykinin B(2) receptor provides therapeutic benefit in hereditary angioedema (HAE) and potentially in many…