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JNJ-7706621

National Institutes of Health

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2019
2019
The Dual Cell Cycle Kinase Inhibitor JNJ-7706621 Reverses Resistance to CD37-Targeted Radioimmunotherapy in Activated B Cell Like Diffuse Large B Cell Lymphoma Cell Lines
The CD37 targeting radioimmunoconjugate 177Lu-lilotomab satetraxetan (Betalutin) is currently being evaluated in a clinical phase… 
2012
2012
Growth suppression and mitotic defect induced by JNJ-7706621, an inhibitor of cyclin-dependent kinases and Aurora kinases
2011
2011
Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase.
We describe in the present paper mutations of the catalytic subunit α of PKA (protein kinase A) that introduce amino acid side… 
2006
2006
Preclinical profile of JNJ-7706621: A dual cyclin dependent kinase and aurora kinase inhibitor
4900 The cyclin dependent kinases (CDKs) and the Aurora kinases play key roles in cell cycle progression and cell division. The… 
2005
2005
The role of human cyclin B1 protein in resistance to the cyclin-dependent kinase inhibitor, JNJ-7706621
Proc Amer Assoc Cancer Res, Volume 46, 2005 4425 Cyclin-dependent kinases (CDKs) are key components involved in cell cycle… 
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