JNJ-26489112

National Institutes of Health

Papers overview

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2016

2016

Timing is everything for sperm assessment in fertility studies.

Dirk Mariën, Graham Paul Bailey, Gary M. Eichenbaum, Sandra De Jonghe
Reproductive toxicology
2016

The fertility study design recommended in the ICH S5(R2) Harmonised Guideline for Detection of Toxicity to Reproduction for… (More)

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Review

2014

Review

2014

Evaluation of JNJ-26489112 in patients with photosensitive epilepsy: a placebo-controlled, exploratory study.

Nicholas A. Di Prospero, Jay J. Gambale, +6 authors Dorothee Kasteleijn-Nolst Trenité
Epilepsy research
2014

PURPOSE To evaluate the activity of JNJ-26489112 in patients with photosensitive epilepsy and determine the doses that result in… (More)

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2014

2014

Implications of retinal effects observed in chronic toxicity studies on the clinical development of a CNS-active drug candidate.

Gary M. Eichenbaum, Junguo Zhou, +11 authors G D Aguirre
Regulatory toxicology and pharmacology : RTP
2014

The development path described for JNJ-26489112 provides perspectives on interpretation of retinal effects observed in… (More)

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2013

2013

Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112).

David F McComsey, Virginia L. Smith-Swintosky, +13 authors Bruce E Maryanoff
Journal of medicinal chemistry
2013

Broad-spectrum anticonvulsants are of considerable interest as antiepileptic drugs, especially because of their potential for… (More)

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