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JG 365

Known as: JG-365 
 

Topic mentions per year

Topic mentions per year

1990-2007
0119902007

Related topics

Related topics

1 relation

Broader (1)

Oligopeptides

Related mentions per year

Related mentions per year

1954-2018
1960198020002020
JG 365
Oligopeptides

Papers overview

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2007
2007
Insights from atomic-resolution X-ray structures of chemically synthesized HIV-1 protease in complex with inhibitors.
The human immunodeficiency virus 1 (HIV-1) protease (PR) is an aspartyl protease essential for HIV-1 viral infectivity. HIV-1 PR… (More)
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2004
2004
X - ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate - based hydroxyethylamine inhibitor ( AIDS / retrovirus / diastereomer…
The structure of a crystal complex of the chemically synthesized protease of human immunodeficiency virus 1 with a heptapeptide… (More)
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2000
2000
Some computational aspects of theoretical anti-HIV drug design.
The three computational methods, the free energy perturbation (FEP), free energy derivative (FED) and continuum solvent molecular… (More)
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1999
1999
[Mechanism of action of aspartic proteases. III. Conformational characteristics of HIV-1 protease inhibitor JG-365].
A set of conformations was shown to be characteristic of the free-state spatial structure of substrate-like inhibitor JG-365 for… (More)
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1996
1996
Empirical free energy calculations of human immunodeficiency virus type 1 protease crystallographic complexes. II. Knowledge-based ligand-protein interaction potentials applied to thermodynamic…
Empirical free energy calculations of HIV-1 protease crystallographic complexes based on the developed knowledge-based ligand… (More)
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1993
1993
Catalytic contribution of flap-substrate hydrogen bonds in "HIV-1 protease" explored by chemical synthesis.
An analogue of "HIV-1 protease" was designed in which the ability to donate important water-mediated hydrogen bonds to substrate… (More)
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1992
1992
New hydroxyethylamine HIV protease inhibitors that suppress viral replication.
The synthesis of analogues of AcSerLeuAsn[Phe-HEA-Pro]IleValOMe (1, JG-365; where HEA stands for the hydroxyethylamine unit 2), a… (More)
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1990
1990
X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor.
The structure of a crystal complex of the chemically synthesized protease of human immunodeficiency virus 1 with a heptapeptide… (More)
Is this relevant?