JB93182
National Institutes of Health
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A new molecular modeling approach has been used to derive a pharmacophore of the potent and selective cholecystokinin-2 (CCK(2…
The systematic optimization of the structure of a novel 2,4,5-trisubstituted imidazole-based cholecystokinin-2 (CCK(2)) receptor…
A series of CCK(2) receptor ligands were analysed with respect to their interaction with binding sites in the membranes of COS-7…
A novel series of nonpeptide CCK(2) receptor antagonists has been prepared, in which 2,7-dioxo-2,3,4,5,6,7-hexahydro-1H-benzo[h…
The previously described complex behaviour of the CCKB/gastrin receptor antagonist, L‐365,260, in radioligand binding assays…
Gastrin stimulates rat stomach enterochromaffin-like (ECL) cells via activation of cholecystokinin-B/gastrin receptors. The…