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JAK2 NP_004963.1:p.V617X

Known as: JAK2 NP_004963.1:p.Val617Xxx, JAK2 p.V617, NP_004963.1:p.Val617Xxx 
A change in the amino acid residue at position 617 in the tyrosine-protein kinase JAK2 protein where valine has been replaced by another amino acid… Expand
National Institutes of Health

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2018
2018
INTRODUCTION Inherited disorders due to rare structural Hb variants are not included in national, neonatal screening tests and… Expand
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2015
2015
Polycythemia vera (PV) is a clonal stem cell disorder characterized by erythrocytosis and associated with burdensome symptoms… Expand
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2013
2013
Emerging evidence indicates that JAK2-STAT3 signaling is frequent in DLBCL cell lines and half of the activated B cell –like (ABC… Expand
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2010
2010
A loss-of-function mutation of TET2, CBL and CEBPA has been implicated in the pathogenesis or leukaemic transformation of… Expand
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Review
2008
Review
2008
The thrombotic and hemorrhagic diathesis represents a frequent complication in myeloproliferative disorders (CMPD). They are… Expand
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2008
2008
Dameshek was wrong.[1][1] In this issue of Blood , in a landmark epidemiologic study, Landgren and colleagues demonstrate that… Expand
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2007
2007
Recently MPLW515 mutations have been reported in osteomyelofibrosis (OMF) and essential thrombocythemia (ET). To further evaluate… Expand
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2007
2007
BackgroundThe chronic myeloproliferative disorders (MPD) are clonal haemopoietic stem cell disorders.AimsThe incidence of JAK2… Expand
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2006
2006
High occurrence of JAK2 V617 mutation in refractory anemia with ringed sideroblasts associated with marked thrombocytosis 
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2006
2006
Discovery of a constitutively activating point mutation of the Janus kinase 2 (JAK2) receptor-associated tyrosine kinase in… Expand
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