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JAK2 NP_004963.1:p.V617X

Known as: JAK2 NP_004963.1:p.Val617Xxx, JAK2 p.V617, NP_004963.1:p.Val617Xxx 
A change in the amino acid residue at position 617 in the tyrosine-protein kinase JAK2 protein where valine has been replaced by another amino acid… 
National Institutes of Health

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JAK2 Gene Mutation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Next generation sequencing redefines a triple negative essential thrombocythaemia as double‐positive with rare mutations on JAK2 V617 and MPL W515 hotspots
Badaloo, A., Jackson, A.A. & Jahoor, F. (1989) Whole body protein turnover and resting metabolic rate in homozygous sickle cell… 
2015
2015
Evolving Therapeutic Options for Polycythemia Vera: Perspectives of the Canadian Myeloproliferative Neoplasms Group.
2013
2013
Lack of JAK2 activating non-synonymous mutations in diffuse large B-cell tumors: JAK2 deregulation still unexplained
Emerging evidence indicates that JAK2-STAT3 signaling is frequent in DLBCL cell lines and half of the activated B cell –like (ABC… 
2010
2010
Methylation of TET2, CBL and CEBPA in Ph-negative myeloproliferative neoplasms
A loss-of-function mutation of TET2, CBL and CEBPA has been implicated in the pathogenesis or leukaemic transformation of… 
Review
2008
Review
2008
An update on the platelet dysfunction in chronic myeloproliferative syndromes.
The thrombotic and hemorrhagic diathesis represents a frequent complication in myeloproliferative disorders (CMPD). They are… 
2007
2007
Detection of Three Different MPLW515 Mutations in 10.1% of All JAK2 V617 Unmutated ET and 9.3% of All JAK2 V617F Unmutated OMF: A Study of 387 Patients.
Recently MPLW515 mutations have been reported in osteomyelofibrosis (OMF) and essential thrombocythemia (ET). To further evaluate… 
2007
2007
Transient jets in V617 Sagittarii
Context. Some of the luminous Compact Binary Supersoft X-Ray sources (CBSS) have shown indications of jets, also called… 
2007
2007
Incidence and significance of the JAK2 V617F mutation in patients with chronic myeloproliferative disorders
BackgroundThe chronic myeloproliferative disorders (MPD) are clonal haemopoietic stem cell disorders.AimsThe incidence of JAK2… 
Highly Cited
2006
Highly Cited
2006
High occurrence of JAK2 V617 mutation in refractory anemia with ringed sideroblasts associated with marked thrombocytosis
High occurrence of JAK2 V617 mutation in refractory anemia with ringed sideroblasts associated with marked thrombocytosis 
2006
2006
MPL W515 and JAK2 V617 mutation analysis in patients with refractory anemia with ringed sideroblasts and an elevated platelet count.
Discovery of a constitutively activating point mutation of the Janus kinase 2 (JAK2) receptor-associated tyrosine kinase in… 
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