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Isosorbide

Known as: D-Glucitol, 1,4:3,6-dianhydro-, Isosorbide [Chemical/Ingredient] 
An organic nitrate with vasodilator activity. Isosorbide relaxes vascular smooth muscle by formation of the free radical nitric oxide (NO), which is… 
National Institutes of Health

Related topics

Related topics

40 relations

Narrower (10)

2,5-dimethylisosorbide2-fluoro-2-deoxyisosorbide 5-mononitrateImdurIsmo
24 HR Isosorbide Mononitrate 60 MG Extended Release Oral Tablet24 HR Isosorbide Mononitrate 60 MG Extended Release Oral Tablet [Imdur]AnemiaAngina Pectoris

Broader (3)

DianhydrosorbitolDiuretics, OsmoticSorbitol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Biobased copolyesters from renewable resources: synthesis and crystallization kinetics of poly(propylene sebacate-co-isosorbide sebacate)
In this work, a series of novel biobased copolymers, poly(propylene sebacate-co-isosorbide sebacate) (P(PSe-co-IS)), were… 
2009
2009
Amphiphilic properties of hydrotropes derived from isosorbide: endo/exo isomeric effects and temperature dependence.
The hydrotropic properties of short-chain monoalkyl ethers of isosorbide have been studied with emphasis on the difference… 
1995
1995
Efficacy of long-term administration of isosorbide for Ménière's disease.
The long-term therapeutic efficacy of isosorbide, an oral hyperosmotic diuretic, was clinically evaluated in 30 patients (14… 
1993
1993
Effects of isosorbide in patients with Menière's disease.
The effects of isosorbide on vertigo, disability, hearing loss and tinnitus in 32 patients with Menière's disease were evaluated… 
1991
1991
Intratympanic gentamicin therapy for Menière's disease placed by a tubal catheter with systematic isosorbide.
In 1974 (6), 6 patients with incapacitating unilateral Meniere's disease were given an empiric treatment with intratympanic… 
1987
1987
Pituitary apoplexy following isosorbide administration.
soon followed by sleep episodes and severe nocturnal dyssomnia. Polysomnography showed short REM sleep latency. The patient was… 
Highly Cited
1987
Highly Cited
1987
Cosolvency and Deviations from Log-Linear Solubilization
The solubilities of three nonpolar drugs, phenytoin, diazepam, and benzocaine, have been measured in 14 cosolvent–water binary… 
1975
1975
Isosorbide in treatment of infantile hydrocephalus.
This paper reports the experiences of the second clinical trial in the use of isosorbide in the treatment of 34 selected cases of… 
1968
1968
The effects of isosorbide on serum and cerebrospinal fluid osmolality and on the spinal fluid pressure in man.
SOSORBIDE is a dihydric alcohol with a molecular weight of 146, formed by the removal of 2 molecules of water from 1 molecule of… 
1965
1965
Isosorbide, a New Oral Osmotic Diuretic
  • Joseph F. TreonLouis E. GongwerWalter H. C. Rueggeberg
  • Proceedings of the Society for Experimental…
  • 1965
  • Corpus ID: 43881224
Summary Isosorbide has been shown to be an effective diuretic when given orally to rats. The urinary output is related to dosage… 
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