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Isolated limb perfusion

Known as: Isolated Chemotherapeutic Limb Perfusion, Limb Perfusion, isolated limb infusion 
A procedure used to deliver anticancer drugs directly to an arm or leg but not to the rest of the body. The flow of blood to and from the limb is… 
National Institutes of Health

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Broader (1)

Infusion procedures
Perfusion of limb

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Endothelial Progenitor Cell-Derived Microvesicles Improve Neovascularization in a Murine Model of Hindlimb Ischemia
Paracrine mediators released from endothelial progenitor cells (EPCs) have been implicated in neoangiogenesis following ischemia… 
Highly Cited
2008
Highly Cited
2008
Isolated Limb Infusion for In-Transit Malignant Melanoma of the Extremity: A Well-Tolerated but Less Effective Alternative to Hyperthermic Isolated Limb Perfusion
BackgroundIsolated limb infusion (ILI) is a recently described minimally invasive technique developed in Australia for delivering… 
Highly Cited
2008
Highly Cited
2008
Outcomes Following Isolated Limb Infusion for Melanoma. A 14-Year Experience
BackgroundIsolated limb infusion (ILI) is a minimally invasive technique for delivering regional chemotherapy in patients with… 
Highly Cited
2005
Highly Cited
2005
Limb salvage with isolated perfusion for soft tissue sarcoma: could less TNF-α be better?
Background: The optimal dose of TNF-a delivered by isolated limb perfusion (ILP) in patients with locally advanced soft tissue… 
Highly Cited
2000
Highly Cited
2000
Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion
Several possible mechanisms for the synergistic anti-tumour effects between tumour necrosis factor alpha (TNF-α) and melphalan… 
Highly Cited
1999
Highly Cited
1999
Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats
An isolated limb perfusion (ILP) model using soft tissue sarcoma-bearing rats was used to study prerequisites for an effective… 
Highly Cited
1998
Highly Cited
1998
Isolated limb infusion with cytotoxic agents: a simple alternative to isolated limb perfusion.
Isolated limb perfusion (ILP) with cytotoxic agents is an effective but complex procedure. Isolated limb infusion (ILI) has been… 
Review
1997
Review
1997
Frequency and duration of remission after isolated limb perfusion for melanoma.
OBJECTIVE To examine the frequency and duration of complete remission for locally recurrent and metastatic limb melanoma after… 
Highly Cited
1996
Highly Cited
1996
Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose…
PURPOSE To evaluate response rates and systemic and regional toxicity of hyperthermic isolated limb perfusion (ILP) for treatment… 
Highly Cited
1990
Highly Cited
1990
Patterns of Cancer in Five Continents
The "Cancer Incidence in Five Continents" series presents data on cancer incidence in a standardized format for every area in the… 
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