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Isolated limb perfusion
Known as:
Isolated Chemotherapeutic Limb Perfusion
, Limb Perfusion
, isolated limb infusion
A procedure used to deliver anticancer drugs directly to an arm or leg but not to the rest of the body. The flow of blood to and from the limb is…
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Infusion procedures
Perfusion of limb
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Treatment of melanoma metastases in a limb by isolated limb perfusion and isolated limb infusion
A. Testori
,
C. Verhoef
,
+4 authors
John F. Thompson
Journal of Surgical Oncology
2011
Corpus ID: 46658307
In‐transit melanoma metastases are often confined to a limb. In this circumstance, treatment by isolated limb perfusion or…
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Review
2004
Review
2004
Isolated limb infusion for melanoma: A simple but effective alternative to isolated limb perfusion
J. Thompson
,
P. Kam
Journal of Surgical Oncology
2004
Corpus ID: 36318927
Multiple limb recurrences sometimes occur in a patient who has had previous surgical treatment for a melanoma on that limb, but…
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2002
2002
Different aspects of hyperthermic isolated limb perfusion
R. J. Ginkel
,
Charles L. H. Berlo
,
+4 authors
Harald J. Hoekstra
2002
Corpus ID: 8650075
The feasibility of hyperthermic isolated limb perfusion (HILP) with tumor necrosis factor-α (TNF) and cisplatin for the…
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Highly Cited
2001
Highly Cited
2001
Isolated limb infusion for melanoma: a simple alternative to isolated limb perfusion.
R. Mian
,
Michael A. Henderson
,
D. Speakman
,
David T. Finkelde
,
J. Ainslie
,
A. Mckenzie
Canadian journal of surgery. Journal canadien de…
2001
Corpus ID: 8285149
OBJECTIVE To describe initial experience with the new technique of isolated limb infusion (ILI) for in-transit melanoma. DESIGN…
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Highly Cited
2001
Highly Cited
2001
Regional toxicity after isolated limb perfusion with melphalan and tumour necrosis factor- alpha versus toxicity after melphalan alone.
B. Vrouenraets
,
A. Eggermont
,
+4 authors
B. Kroon
European Journal of Surgical Oncology
2001
Corpus ID: 10872703
AIMS To determine whether the addition of high-dose tumour necrosis factor-alpha (TNF alpha) to isolated limb perfusion (ILP…
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Highly Cited
2000
Highly Cited
2000
TNF- α augments intratumoural concentrations of doxorubicin in TNF- α -based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects
AH van der Veen
,
J.H.W. de Wilt
,
A. Eggermont
,
ST van Tiel
,
A. Seynhaeve
,
T. T. Hagen
British Journal of Cancer
2000
Corpus ID: 12211657
We have shown previously that isolated limb perfusion (ILP) in sarcoma-bearing rats results in high response rates when melphalan…
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Highly Cited
1999
Highly Cited
1999
Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats
J.H.W. de Wilt
,
E. Manusama
,
ST van Tiel
,
Mga van Ijken
,
T. T. Hagen
,
A. Eggermont
British Journal of Cancer
1999
Corpus ID: 16582328
An isolated limb perfusion (ILP) model using soft tissue sarcoma-bearing rats was used to study prerequisites for an effective…
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Highly Cited
1997
Highly Cited
1997
Isolated limb reperfusion with tumor necrosis factor and melphalan in patients with extremity melanoma after failure of isolated limb perfusion with chemotherapeutics
D. Bartlett
,
Grace Ma
,
H. Alexander
,
S. Libutti
,
D. Fraker
Cancer
1997
Corpus ID: 35628117
This retrospective study evaluated the benefit of using tumor necrosis factor (TNF) and melphalan administered via an isolated…
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Highly Cited
1993
Highly Cited
1993
Low‐dose tumour necrosis factor α and melphalan in hyperthermic isolated limb perfusion
S. Hill
,
W. J. Fawcett
,
J. Sheldon
,
N. Soni
,
W. Tr
,
J. Thomas
1993
Corpus ID: 72306649
Nine patients with soft tissue tumours of the lower limb not amenable to treatment other than by isolated limb perfusion or…
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1990
1990
Isolated limb perfusion for localized melanoma of the extremity. A matched comparison of wide local excision with isolated limb perfusion and wide local excision alone.
M. Edwards
,
S. Soong
,
A. Boddie
,
C. Balch
,
C. McBride
Archives of Surgery
1990
Corpus ID: 40042340
The therapeutic efficacy of isolated limb perfusion in patients with localized melanoma of the extremity remains controversial…
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