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Isodesmosine

Known as: Isodesmosine [Chemical/Ingredient], Pyridinium, 2-(4-amino-4-carboxybutyl)-1-(5-amino-5-carboxypentyl)-3,5-bis(3-amino-3-carboxypropyl)- 
2-(4-Amino-4-carboxybutyl)-1-(5-amino-5-carboxypentyl)-3,5-bis(3-amino-3-carboxypropyl)pyridinium. A rare amino acid found in elastin, formed by… Expand
National Institutes of Health

Papers overview

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2011
2011
The development of atherosclerotic lesions and abdominal aortic aneurysms involves degradation and loss of extracellular matrix… Expand
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Highly Cited
2011
Highly Cited
2011
The aim of this study is to develop a standardized LC-MS/MS method for accurate measurement of desmosine (DES) and isodesmosine… Expand
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2009
2009
Background— Chronic renal failure (CRF) is associated with cardiac dysfunction and increased aortic stiffness. The mechanisms… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVES Application of mass spectrometry (MS) for direct measurements of desmosine (D) and isodesmosine (I) in urine, plasma… Expand
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Highly Cited
2003
Highly Cited
2003
Desmosine (D) and isodesmosine (I), the intramolecular crosslinking amino acids that occur in chains of elastin, have now been… Expand
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Highly Cited
2000
Highly Cited
2000
Degradation of extracellular matrix components is central to many pathological features of chronic destructive lung disorders… Expand
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE Extracellular matrix, particularly type I fibrillar collagen, provides tensile strength that allows cardiac muscle to… Expand
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Highly Cited
1993
Highly Cited
1993
Abstract. The measurement of the 3–OH pyridinium compounds, pyridinoline (Pyr) and deoxypyridinoline (Dpyr), in urine by high… Expand
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Highly Cited
1977
Highly Cited
1977
  • B. Starcher
  • Analytical biochemistry
  • 1977
  • Corpus ID: 36268890
Abstract A method is described for measuring the elastin content of whole tissue. Desmosine and isodesmosine, the cross-linking… Expand
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Highly Cited
1971
Highly Cited
1971
Elastin preparations from intimal layers and the media of normal and atherosclerotic human aortae were analyzed for protein and… Expand
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