Intestinal Intraepithelial Neoplasia
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BACKGROUND & AIMS
Altered gut microbiota is implicated in development of colorectal cancer (CRC). Some intestinal bacteria have… Expand Coordination of stem cell activity with inflammatory responses is critical for regeneration and homeostasis of barrier epithelia… Expand Regenerative processes are critical to maintain tissue homeostasis in high-turnover tissues. At the same time, proliferation of… Expand US28 is a constitutively active chemokine receptor encoded by CMV (also referred to as human herpesvirus 5), a highly prevalent… Expand Accumulating evidence suggests that hyperproliferating intestinal stem cells (SCs) and progenitors drive cancer initiation… Expand The mechanisms that regulate mammalian organ size are poorly understood. It is unclear whether the pathways that control organ… Expand The isolated homeobox gene Enx (Hox11L1) is expressed in enteric neurons innervating distal ileum, and proximal and distal colon… Expand To investigate the role of genetic instability in the development of intestinal‐ and diffuse‐type gastric cancers, six… Expand One hundred seventy-eight of 326 patients had surgery for Hirschsprung's disease at Red Cross Children's Hospital (1957 to 1990… Expand Neuronal intestinal dysplasia is characterized by structural changes consisting of hyperplasia of the myenteric plexus, an… Expand