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Intestinal Intraepithelial Neoplasia

Known as: Bowel Dysplasia, Intestinal Dysplasia 
A precancerous neoplastic process that affects the small or large intestine. It is characterized by low or high grade dysplasia of the mucosal… Expand
National Institutes of Health

Related topics

Related topics

9 relations
Epithelial CellsEpitheliumGastrointestinal systemGlandular cell
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice.
BACKGROUND & AIMS Altered gut microbiota is implicated in development of colorectal cancer (CRC). Some intestinal bacteria have… Expand
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Highly Cited
2010
Highly Cited
2010
Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila
Regenerative processes are critical to maintain tissue homeostasis in high-turnover tissues. At the same time, proliferation of… Expand
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Highly Cited
2010
Highly Cited
2010
Grading of gastric foveolar-type dysplasia in Barrett's esophagus
Dysplasia is the gold standard biomarker of cancer risk in Barrett's esophagus, but its diagnosis remains difficult. This is due… Expand
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Highly Cited
2009
Highly Cited
2009
Synergy between bacterial infection and genetic predisposition in intestinal dysplasia
Accumulating evidence suggests that hyperproliferating intestinal stem cells (SCs) and progenitors drive cancer initiation… Expand
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Highly Cited
2007
Highly Cited
2007
YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells
The mechanisms that regulate mammalian organ size are poorly understood. It is unclear whether the pathways that control organ… Expand
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Highly Cited
2006
Highly Cited
2006
Epidemiology of congenital innervation defects of the distal colon
Congenital colorectal innervation defects were evaluated by studying 3699 colonic mucosal biopsy specimens obtained from 773… Expand
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Highly Cited
1997
Highly Cited
1997
A novel pathogenesis of megacolon in Ncx/Hox11L.1 deficient mice.
The Ncx/Hox11L.1 gene, a member of the Hox11 homeobox gene family, is mainly expressed in neural crest-derived tissues. To… Expand
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Highly Cited
1997
Highly Cited
1997
Enx (Hox11L1)-deficient mice develop myenteric neuronal hyperplasia and megacolon
The isolated homeobox gene Enx (Hox11L1) is expressed in enteric neurons innervating distal ileum, and proximal and distal colon… Expand
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Highly Cited
1994
Highly Cited
1994
Long-term clinical, manometric, and histological evaluation of obstructive symptoms in the postoperative Hirschsprung's patient.
One hundred seventy-eight of 326 patients had surgery for Hirschsprung's disease at Red Cross Children's Hospital (1957 to 1990… Expand
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Highly Cited
1981
Highly Cited
1981
Localized and disseminated forms of neuronal intestinal dysplasia mimicking Hirschsprung's disease.
Neuronal intestinal dysplasia is characterized by structural changes consisting of hyperplasia of the myenteric plexus, an… Expand
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