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Intermediate-Conductance Calcium-Activated Potassium Channels

Known as: Potassium Channels, IK, Intermediate Conductance Calcium Activated Potassium Channels, Potassium Channels, Intermediate-Conductance Calcium-Activated 
A major class of calcium-activated potassium channels that were originally discovered in ERYTHROCYTES. They are found primarily in non-excitable… (More)
National Institutes of Health

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Topic mentions per year

1964-2018
0204019642018

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In BloodKCNN4 geneProcess of secretionagonists
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Kcnn4 protein, mouse

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Intermediate-Conductance Calcium-Activated Potassium Channels
physiological aspects
In Blood
chemical synthesis
KCNN4 gene
standards characteristics

Papers overview

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2011
2011
Intermediate-conductance calcium-activated potassium channels participate in neurovascular coupling.
BACKGROUND AND PURPOSE Controlling vascular tone involves K(+) efflux through endothelial cell small- and intermediate… (More)
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2010
2010
Obesity up-regulates intermediate conductance calcium-activated potassium channels and myoendothelial gap junctions to maintain endothelial vasodilator function.
The mechanisms involved in altered endothelial function in obesity-related cardiovascular disease are poorly understood. This… (More)
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2007
2007
Dihydropyridines inhibit acetylcholine-induced hyperpolarization in cochlear artery via blockade of intermediate-conductance calcium-activated potassium channels.
Acetylcholine (ACh) induces hyperpolarization and dilation in a variety of blood vessels, including the cochlear spiral modiolar… (More)
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Highly Cited
2006
Highly Cited
2006
Spatial separation of endothelial small- and intermediate-conductance calcium-activated potassium channels (K(Ca)) and connexins: possible relationship to vasodilator function?
Activation of endothelial cell small- (S) and intermediate- (I) conductance calcium-activated potassium channels (K(Ca)) and… (More)
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2005
2005
A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes.
We investigated the role of small-conductance calcium-activated potassium (SK) and intermediate-conductance calcium-activated… (More)
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2004
2004
Block of maurotoxin and charybdotoxin on human intermediate-conductance calcium-activated potassium channels (hIKCa1).
Using human intermediate-conductance calcium-activated potassium (hIKCa1) channels as a model we aimed to characterize structural… (More)
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2003
2003
Maurotoxin: A Potent Inhibitor of Intermediate Conductance Ca -Activated Potassium Channels
Maurotoxin, a 34-amino acid toxin from Scorpio maurus scorpion venom, was examined for its ability to inhibit cloned human SK… (More)
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2000
2000
Effects of inhibitors of small- and intermediate-conductance calcium-activated potassium channels, inwardly-rectifying potassium channels and Na(+)/K(+) ATPase on EDHF relaxations in the rat hepatic…
1. In the rat hepatic artery, the SK(Ca) inhibitors UCL 1684 (300 nM) completely blocked, and scyllatoxin (1 microM) and d… (More)
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Highly Cited
1998
Highly Cited
1998
Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits
Large-conductance calcium-activated potassium channels (maxi-K channels) have an essential role in the control of excitability… (More)
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Highly Cited
1984
Highly Cited
1984
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones
Acidic amino acids are putative excitatory synaptic transmitters1,2, the ionic mechanism of which is not well understood. Recent… (More)
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