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Interleukin-16, human

Known as: Interleukin-16, IL16, Lymphocyte Chemoattractant Factor 
Interleukin-16 (121 aa, ~12 kDa) is encoded by the human IL16 gene. This protein plays a role in leukocyte chemotaxis.
National Institutes of Health

Related topics

Related topics

14 relations
Cell Proliferation Regulatory ProcessChemotaxisCytokine GeneCytokine Network Pathway

Broader (1)

Interleukin-16

Papers overview

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2013
2013
Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages.
The RNA-binding protein tristetraprolin (TTP) destabilizes target messenger RNAs (mRNAs) containing AU-rich elements within their… 
Highly Cited
2009
Highly Cited
2009
Intake of meat, meat mutagens, and iron and the risk of breast cancer in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Background:Epidemiological evidence on meat intake and breast cancer is inconsistent, with little research on potentially… 
2004
2004
Expression of interleukin-16 by microglial cells in inflammatory, autoimmune, and degenerative lesions of the rat brain
2003
2003
The -295T-to-C promoter polymorphism of the IL-16 gene is associated with Crohn's disease.
Highly Cited
2003
Highly Cited
2003
Demonstration of the Presence of IL‐16, IL‐17 and IL‐18 at the Murine Fetomaternal Interface during Murine Pregnancy
PROBLEM:  To determine if interleukin‐16 (IL‐16), IL‐17, and IL‐18 are present at the murine fetomaternal interface during… 
Highly Cited
2002
Highly Cited
2002
Expression of Transcription Factor AML-2 (RUNX3, CBFα-3) Is Induced by Epstein-Barr Virus EBNA-2 and Correlates with the B-Cell Activation Phenotype
ABSTRACT To identify cell proteins regulated by the Epstein-Barr virus (EBV) transcription factor EBNA-2, we analyzed a cell line… 
Highly Cited
2001
Highly Cited
2001
Nuclear Translocation of the N-terminal Prodomain of Interleukin-16*
Interleukin-16 (IL-16) is a pleiotropic cytokine that functions as a chemoattractant factor, a modulator of T cell activation… 
2000
2000
A new polymorphism in the promoter region of the human interleukin-16 (IL-16) gene
Interleukin 16 (IL-16) is a chemotactic cytokine which binds to CD4 and affects T cell activation. Here we report a novel single… 
Highly Cited
1998
Highly Cited
1998
Circulating interleukin-16 in systemic lupus erythematosus.
OBJECTIVE To investigate the relationship between interleukin (IL)-16 and systemic lupus erythematosus (SLE). METHODS Serum… 
Review
1998
Review
1998
Signaling and functional properties of interleukin-16.
Interleukin-16 is secreted from a variety of immune cells as a peptide of 17 kDa which aggregates into tetrameric form essential… 
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