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Interleukin-13 Receptor alpha1 Subunit

Known as: Antigen, CD213a1, CD213a1 Antigens, Interleukin-13 Receptor alpha1 Subunit [Chemical/Ingredient] 
An interleukin receptor subunit with specificity for INTERLEUKIN-13. It dimerizes with the INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT to form the TYPE II… Expand
National Institutes of Health

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IL13RA1 geneIn Bloodagonistsantagonists & inhibitors
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IL13RA1 protein, human

Papers overview

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Highly Cited
2009
Highly Cited
2009
MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression 1
Allergic airway inflammation is characterized by marked in situ changes in gene and protein expression, yet the role of microRNAs… Expand
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Review
2009
Review
2009
Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells.
Immunity in the newborn is characterized by minimal T helper (Th)1 function but an excess of Th2 activity. Since Th1 lymphocytes… Expand
Highly Cited
2008
Highly Cited
2008
Distinct roles for IL-13 and IL-4 via IL-13 receptor α1 and the type II IL-4 receptor in asthma pathogenesis
IL-13 and IL-4 are central T helper 2 (Th2) cytokines in the immune system and potent activators of inflammatory responses and… Expand
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Highly Cited
2006
Highly Cited
2006
The IL-21 receptor augments Th2 effector function and alternative macrophage activation.
The IL-21 receptor (IL-21R) shows significant homology with the IL-4R, and CD4+ Th2 cells are an important source of IL-21. Here… Expand
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Review
2003
Review
2003
IL-13 receptors and signaling pathways: an evolving web.
  • G. Hershey
  • The Journal of allergy and clinical immunology
  • 2003
    • Corpus ID: 24312649
IL-13 is an immunoregulatory cytokine secreted predominantly by activated T(H)2 cells. Over the past several years, it has become… Expand
Review
2002
Review
2002
Structure, binding, and antagonists in the IL-4/IL-13 receptor system.
Interleukin-4 (IL-4) and IL-13 are the only cytokines known to bind to the receptor chain IL-4Ralpha. Receptor sharing by these… Expand
Highly Cited
2001
Highly Cited
2001
The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway.
The interleukin-13 receptor (IL-13R) complex is composed of 2 different chains, IL-13Ralpha1 (also known as IL-13Ralpha') and IL… Expand
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Highly Cited
2001
Highly Cited
2001
Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma.
Hodgkin lymphoma (HL) is characterized by the abnormal expression of multiple cytokines, accounting for its unique… Expand
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Highly Cited
2000
Highly Cited
2000
Genetic variants of IL-13 signalling and human asthma and atopy.
Asthma and atopy show epidemiological association and are biologically linked by T-helper type 2 (T(h)2) cytokine-driven… Expand
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Highly Cited
1998
Highly Cited
1998
Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.
Airway hyperresponsiveness leading to subepithelial fibrosis is mediated by inflammatory cells activated by T helper (Th) 2… Expand
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