Interleukin-13 Receptor alpha1 Subunit

Known as: Antigen, CD213a1, CD213a1 Antigens, Interleukin-13 Receptor alpha1 Subunit [Chemical/Ingredient] 
An interleukin receptor subunit with specificity for INTERLEUKIN-13. It dimerizes with the INTERLEUKIN-4 RECEPTOR ALPHA SUBUNIT to form the TYPE II… (More)
National Institutes of Health

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1977-2015
05101519772015

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IL13RA1 geneIn Bloodagonistsantagonists & inhibitors
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IL13RA1 protein, human

Related mentions per year

Related mentions per year

1936-2019
19401960198020002020
Interleukin-13 Receptor alpha1 Subunit
physiological aspects
agonists
IL13RA1 protein, human
IL13RA1 gene
In Blood

Papers overview

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Highly Cited
2009
Highly Cited
2009
MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression.
Allergic airway inflammation is characterized by marked in situ changes in gene and protein expression, yet the role of microRNAs… (More)
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2007
2007
Genetic association studies of interleukin-13 receptor alpha1 subunit gene polymorphisms in asthma and atopy.
Interleukin (IL)-13 plays a central role in asthma pathogenesis by binding to the IL-13 receptor, which is a heterodimer composed… (More)
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Highly Cited
2007
Highly Cited
2007
Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1.
The Zaire ebolavirus protein VP24 was previously demonstrated to inhibit alpha/beta interferon (IFN-alpha/beta)- and IFN-gamma… (More)
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Highly Cited
2006
Highly Cited
2006
The IL-21 receptor augments Th2 effector function and alternative macrophage activation.
The IL-21 receptor (IL-21R) shows significant homology with the IL-4R, and CD4+ Th2 cells are an important source of IL-21. Here… (More)
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Highly Cited
2005
Highly Cited
2005
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution.
BACKGROUND & AIMS Ulcerative colitis (UC) is characterized by a Th2 immune response with inflammation and epithelial barrier… (More)
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Highly Cited
2003
Highly Cited
2003
Enhanced Interleukin (IL)-13 Responses in Mice Lacking IL-13 Receptor α 2
Interleukin (IL)-13 has recently been shown to play important and unique roles in asthma, parasite immunity, and tumor recurrence… (More)
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2002
2002
Kinetic analysis of the interleukin-13 receptor complex.
Interleukin (IL)-13 is a key cytokine associated with the asthmatic phenotype. It signals via its cognate receptor, a complex of… (More)
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Highly Cited
2001
Highly Cited
2001
The interleukin-13 receptor alpha2 chain: an essential component for binding and internalization but not for interleukin-13-induced signal transduction through the STAT6 pathway.
The interleukin-13 receptor (IL-13R) complex is composed of 2 different chains, IL-13Ralpha1 (also known as IL-13Ralpha') and IL… (More)
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Highly Cited
2000
Highly Cited
2000
Genetic variants of IL-13 signalling and human asthma and atopy.
Asthma and atopy show epidemiological association and are biologically linked by T-helper type 2 (T(h)2) cytokine-driven… (More)
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Highly Cited
1998
Highly Cited
1998
Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.
Airway hyperresponsiveness leading to subepithelial fibrosis is mediated by inflammatory cells activated by T helper (Th) 2… (More)
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