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Interleukin-10 Receptor alpha Subunit

Known as: IL 10R1 Receptor, Interleukin-10 Receptor alpha Subunit [Chemical/Ingredient], Interleukin 10 Receptor alpha Chain 
A subunit of the interleukin-10 receptor. It plays a role in receptor signaling by associating with JANUS KINASE 1.
National Institutes of Health

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Papers overview

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2015
2015
Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery
High-Throughput (HT) SELEX combines SELEX (Systematic Evolution of Ligands by EXponential Enrichment), a method for aptamer… Expand
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2012
2012
Exome sequencing identifies novel compound heterozygous mutations of IL-10 receptor 1 in neonatal-onset Crohn's disease
Inflammatory bowel disease is well recognized for a strong genetic involvement in its pathogenesis. Homozygous mutations in… Expand
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2012
2012
Identification and molecular characterization of the interleukin-10 receptor 1 of the zebrafish (Danio rerio) and the goldfish (Carassius auratus L.).
This is the first report of the identification and molecular characterization of an interleukin-10 receptor 1 in bony fish. By… Expand
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2012
2012
Expression and possible role of interleukin-10 receptors in patients with adenomyosis.
OBJECTIVE To investigate the expression and potential roles of interleukin-10 receptor 1 (IL-10R1) and interleukin-10 receptor 2… Expand
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2012
2012
Anti-interleukin-10R1 monoclonal antibody enhances bacillus Calmette-Guérin induced T-helper type 1 immune responses and antitumor immunity in a mouse orthotopic model of bladder cancer.
PURPOSE Proper induction of the T-helper type 1 immune response is required for effective bacillus Calmette-Guérin immunotherapy… Expand
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2010
2010
Interleukin 10 receptor alpha subunit (IL-10RA) gene polymorphism and IL-10 serum levels in Egyptian atopic patients.
OBJECTIVES To assess the value of serum interleukin (IL) 10 levels as an immunological marker in atopy and to determine the role… Expand
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2008
2008
Human interleukin 10 receptor 1/IgG1-Fc fusion proteins: immunoadhesins for human IL-10 with therapeutic potential
Interleukin 10 (IL-10) is produced by various types of human cancer, including malignant melanoma, and plays an important role in… Expand
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2007
2007
Homozygosity of the interleukin-10 receptor 1 G330R allele is associated with schizophrenia.
Infections of unknown origin and an altered immune response have been hypothesized to play a role in the pathogenesis of… Expand
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2005
2005
Polymorphism of the mouse gene for the interleukin 10 receptor alpha chain (Il10ra) and its association with the autoimmune phenotype
Several studies suggest that interleukin (IL)-10 pathway is involved in murine lupus, while no linkage of IL-10 gene polymorphism… Expand
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2005
2005
Bi-allelic presence of the interleukin-10 receptor 1 G330R allele is associated with cirrhosis in chronic HCV-1 infection
Immune response to viral infection is an important determinant of liver injury in chronic hepatitis C (CHC). Experimental and… Expand
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