Skip to search formSkip to main contentSkip to account menu

Inosine triphosphate pyrophosphatase

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Structural dynamics of inosine triphosphate pyrophosphatase (ITPA) protein and two clinically relevant mutants: molecular dynamics simulations
Abstract The inosine triphosphate pyrophosphatase (ITPA) protein is responsible for removing noncanonical purine nucleoside… 
2016
2016
The impact of an inosine triphosphate pyrophosphatase genotype on bilirubin increase in chronic hepatitis C patients treated with simeprevir, pegylated interferon plus ribavirin
AbstractBackground Hyperbilirubinemia, mild or moderate, is a commonly observed laboratory abnormality in chronic hepatitis C… 
Review
2013
Review
2013
Management of anemia induced by triple therapy in patients with chronic hepatitis C: challenges, opportunities and recommendations.
2013
2013
Effect of gender and ITPA polymorphisms on ribavirin-induced anemia in chronic hepatitis C patients.
2012
2012
Determination of Inosine Triphosphate Pyrophosphatase Phenotype in Human Red Blood Cells Using HPLC
Background: Thiopurine drugs, widely used in cancer chemotherapy, inflammatory bowel disease, and autoimmune hepatitis, are… 
2012
2012
Efficacy of splenectomy in preventing anemia in patients with recurrent hepatitis C following liver transplantation is not dependent on inosine triphosphate pyrophosphatase genotype
Aim:  A genetic polymorphism of inosine triphosphate pyrophosphatase (ITPA) has been associated with pegylated‐interferon… 
2011
2011
Association Between Adverse Effects Under Azathioprine Therapy and Inosine Triphosphate Pyrophosphatase Activity in Patients With Chronic Inflammatory Bowel Disease
Background: Inosine triphosphate pyrophosphatase (ITPA) catalyzes the pyrophosphohydrolysis of inosine triphosphate to inosine… 
Highly Cited
2011
Highly Cited
2011
A pharmacogenetics study of TPMT and ITPA genes detects a relationship with side effects and clinical response in patients with inflammatory bowel disease receiving Azathioprine.
BACKGROUND AND AIMS Pharmacogenetic studies in inflammatory bowel diseases (IBD) are mainly focused on genes involved in the… 
2011
2011
Polymorphism of the inosine triphosphate pyrophosphatase gene predicts ribavirin-induced anemia in chronic hepatitis C patients.
Ribavirin (RBV)-induced anemia is a serious side effect of pegylated interferon (PEG-IFN) plus RBV therapy which is the standard… 
Review
2010
Review
2010
Inosine triphosphate pyrophosphatase 94C> A polymorphism: clinical implications for patients with systemic lupus erythematosus treated with azathioprine
Importance of the field: Azathioprine (AZA) has immunosuppressive property and has been widely used in organ transplantation and… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)