Infiltration

The concept that progression of cancer is regulated by interactions of cancer cells with their microenvironment was postulated by… Expand

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS), which gives rise to… Expand

Importance Enasidenib mesylate, a mutant isocitrate dehydrogenase 2 (IDH2) protein inhibitor that promotes differentiation of… Expand

By exerting pro- and anti-tumorigenic actions, tumor-infiltrating immune cells can profoundly influence tumor progression, as… Expand

Tissue damage and inflammation are important triggers for regeneration and fibrosis. Tissue damage not only induces inflammation… Expand

Programmed cell death protein 1 (PD-1) blockade targeting the PD-1 immune checkpoint has demonstrated unprecedented clinical… Expand

Background - The presence of tumor-infiltrating lymphocytes (TILs) in the tumor microenvironment is associated with an improved… Expand

Small-cell lung cancer (SCLC) is an aggressive malignancy associated with a poor prognosis. First-line treatment has remained… Expand

Assessment of the immune response to tumors is growing in importance as the prognostic implications of this response are… Expand

Monocyte chemoattractant/chemotactic protein-1 (MCP-1), a member of the CC chemokine family, is one of the key chemokines that… Expand