FAQ

Imprinting Gene

A gene that does not exhibit equal expression of both alleles due to repression or inactivation, resulting in the genetic non-equivalence of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2017
01219972017

Papers overview

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2018
2018
Epigenetic alterations contribute to promoter activity of imprinting gene IGF2.
The expression of insulin-like growth factor 2 (IGF2), a classical imprinting gene, didn't completely correlate with its… (More)
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2016
2016
Embryos aggregation improves development and imprinting gene expression in mouse parthenogenesis.
Mouse parthenogenetic embryonic stem cells (PgESCs) could be applied to study imprinting genes and are used in cell therapy. Our… (More)
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2015
2015
Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma
The enhancer of zeste homolog 2 (EZH2) methyltransferase is the catalytic subunit of polycomb repressive complex 2 (PRC2), which… (More)
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2012
2012
The imprinted H19 gene regulates human placental trophoblast cell proliferation via encoding miR-675 that targets Nodal Modulator 1 (NOMO1).
Preeclampsia is a pregnancy-specific syndrome mainly characterized by hypertensive disorder and proteinuria after gestational… (More)
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Highly Cited
2009
Highly Cited
2009
Clone- and gene-specific aberrations of parental imprinting in human induced pluripotent stem cells.
Genomic imprinting is an epigenetic phenomenon whereby genes are expressed in a monoallelic manner, which is inherited either… (More)
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2009
2009
[VIGILIN involves in regulation of imprinting gene IGF2 and H19 in human hepatocellular carcinoma cell].
OBJECTIVE To explore possible relationship among expression of human high density lipoprotein binding protein(VIGILIN), H19 and… (More)
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Highly Cited
2004
Highly Cited
2004
DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction.
In mammals, the resetting of DNA methylation patterns in early embryos and germ cells is crucial for development. Two DNA… (More)
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Highly Cited
2003
Highly Cited
2003
A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells.
Human pituitary adenomas are the most common intracranial neoplasm. Typically monoclonal in origin, a somatic mutation is a… (More)
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2003
2003
Regulation of the H19 imprinting gene expression in human nasopharyngeal carcinoma by methylation.
In East Asia and Singapore, the human nasopharyngeal carcinoma (NPC) presented clinically is mainly of the undifferentiated type… (More)
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1997
1997
Relaxation of imprinting of human insulin-like growth factor II gene, IGF2, in sporadic breast carcinomas.
Breast cancer is the most frequent malignancy in women and genetically heterogeneous, and a variety of genetic lesions have been… (More)
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