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Immunoglobulin Superfamily Member 8

Known as: CD81 Partner 3, Glu-Trp-Ile EWI Motif-Containing Protein 2, Keratinocytes-Associated Transmembrane Protein 4 
Immunoglobulin superfamily member 8 (613 aa, ~65 kDa) is encoded by the human IGSF8 gene. This protein is involved in the regulation of cellular… 
National Institutes of Health

Related topics

Related topics

8 relations
Cell ProliferationCellular MembraneGenes, RegulatorIGSF8 gene

Papers overview

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Review
2019
Review
2019
CO, H2O, H2O+ line and dust emission in a z = 3.63 strongly lensed starburst merger at sub-kiloparsec scales
Using the Atacama Large Millimeter/submillimeter Array (ALMA), we report high angular-resolution observations of the redshift z… 
2015
2015
EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis
In normal melanocytes, TGF-β signaling has a cytostatic effect. However, in primary melanoma cells, TGF-β-induced cytostasis is… 
2014
2014
GLP‐1 and peptide YY secretory response after fat load is impaired by insulin resistance, impaired fasting glucose and type 2 diabetes in morbidly obese subjects
Both glucagon‐like peptide‐1 (GLP‐1) and peptide YY (PYY) are gut hormones involved in energy homoeostasis. Obesity, insulin… 
2009
2009
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.
EWI-2, a cell surface IgSF protein, is highly expressed in normal human brain but is considerably diminished in glioblastoma… 
Highly Cited
2009
Highly Cited
2009
Mutation of juxtamembrane cysteines in the tetraspanin CD81 affects palmitoylation and alters interaction with other proteins at the cell surface.
Highly Cited
2003
Highly Cited
2003
EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells.
Several tetraspanins bind directly to a few molecular partners to form primary complexes, which might assemble through… 
Highly Cited
2001
Highly Cited
2001
EWI-2 Is a Major CD9 and CD81 Partner and Member of a Novel Ig Protein Subfamily*
A novel Ig superfamily protein, EWI-2, was co-purified with tetraspanin protein CD81 under relatively stringent Brij 96 detergent… 
1997
1997
Passage d'une expression rationnelle à un automate fini non-déterministe
Resume Le but de cet article est de presenter un nouvel algorithme sequentiel en temps Ω(n2) pour la conversion d’une expression… 
1997
1997
Detection of APGWamide-like immunoreactivity in the sea scallop, Placopecten magellanicus
1996
1996
Wapiti home range and movement patterns in a sagebrush desert
Strohmeyer and Peek "Wapiti home range and movement patterns in a sagebrush desert." Northwest Science. 1996; 70(2): 79-87 
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