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Immunoglobulin Superfamily Member 8

Known as: CD81 Partner 3, Glu-Trp-Ile EWI Motif-Containing Protein 2, Keratinocytes-Associated Transmembrane Protein 4 
Immunoglobulin superfamily member 8 (613 aa, ~65 kDa) is encoded by the human IGSF8 gene. This protein is involved in the regulation of cellular… Expand
National Institutes of Health

Related topics

Related topics

8 relations
Cell ProliferationCellular MembraneGenes, RegulatorIGSF8 gene
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis
In normal melanocytes, TGF-β signaling has a cytostatic effect. However, in primary melanoma cells, TGF-β-induced cytostasis is… Expand
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2014
2014
GLP‐1 and peptide YY secretory response after fat load is impaired by insulin resistance, impaired fasting glucose and type 2 diabetes in morbidly obese subjects
Both glucagon‐like peptide‐1 (GLP‐1) and peptide YY (PYY) are gut hormones involved in energy homoeostasis. Obesity, insulin… Expand
2009
2009
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.
EWI-2, a cell surface IgSF protein, is highly expressed in normal human brain but is considerably diminished in glioblastoma… Expand
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2009
2009
Mutation of juxtamembrane cysteines in the tetraspanin CD81 affects palmitoylation and alters interaction with other proteins at the cell surface.
Palmitoylation of tetraspanins affects protein-protein interactions, suggesting a key role in the assembly of the tetraspanin web… Expand
2005
2005
Warm-Dense Molecular Gas in the ISM of Starbursts, LIRGs and ULIRGs
The role of star formation in luminous and ultraluminous infrared galaxies (LIRGs, LIR 10 L ; ULIRGs, LIR 10 L ) is a hotly… Expand
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Highly Cited
2003
Highly Cited
2003
EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells.
Several tetraspanins bind directly to a few molecular partners to form primary complexes, which might assemble through… Expand
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Highly Cited
2001
Highly Cited
2001
EWI-2 Is a Major CD9 and CD81 Partner and Member of a Novel Ig Protein Subfamily*
A novel Ig superfamily protein, EWI-2, was co-purified with tetraspanin protein CD81 under relatively stringent Brij 96 detergent… Expand
1997
1997
Passage d'une expression rationnelle à un automate fini non-déterministe
Resume Le but de cet article est de presenter un nouvel algorithme sequentiel en temps Ω(n2) pour la conversion d’une expression… Expand
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1997
1997
Detection of APGWamide-like immunoreactivity in the sea scallop, Placopecten magellanicus
In pulmonate gastropods, the peptide, Ala-Pro-Gly-Trp-NH2 (APGWamide), appears to be located nearly exclusively in the neural… Expand
1996
1996
Wapiti home range and movement patterns in a sagebrush desert
Strohmeyer and Peek "Wapiti home range and movement patterns in a sagebrush desert." Northwest Science. 1996; 70(2): 79-87 
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