FAQ

Immunoglobulin Superfamily Member 8

Known as: CD81 Partner 3, Glu-Trp-Ile EWI Motif-Containing Protein 2, Keratinocytes-Associated Transmembrane Protein 4 
Immunoglobulin superfamily member 8 (613 aa, ~65 kDa) is encoded by the human IGSF8 gene. This protein is involved in the regulation of cellular… (More)

Topic mentions per year

Topic mentions per year

2001-2017
01220012017

Related topics

Related topics

7 relations
Cell ProliferationCellular MembraneGenes, RegulatorIGSF8 gene
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Related mentions per year

Related mentions per year

1944-2018
19401960198020002020
Immunoglobulin Superfamily Member 8
Cell Proliferation
cell motility
Genes, Regulator
Integral Membrane Proteins
Transmembrane Domain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Differential expression of EWI-2 in endometriosis, its functional role and underlying molecular mechanisms.
AIM We aimed to investigate EWI-2 expression in endometrium tissues collected from women with endometriosis at mRNA and protein… (More)
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2015
2015
EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis
In normal melanocytes, TGF-β signaling has a cytostatic effect. However, in primary melanoma cells, TGF-β-induced cytostasis is… (More)
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2013
2013
Tetraspanins are involved in Schwann cell-axon interaction.
Many studies have shown that tetraspanins play important role in cell-cell and cell-extracellular matrix (ECM) interactions. The… (More)
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2011
2011
Targeting of Breast Cancer through MT1-MMP/Tetraspanin Complexes W81XWH-08-1-0179
EWI-2, a cell surface IgSF protein, is highly expressed in normal human brain but is considerably diminished in glioblastoma… (More)
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2009
2009
The Ig domain protein CD9P-1 down-regulates CD81 ability to support Plasmodium yoelii infection.
Invasion of hepatocytes by Plasmodium sporozoites is a prerequisite for establishment of a malaria natural infection. The… (More)
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2009
2009
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo.
EWI-2, a cell surface IgSF protein, is highly expressed in normal human brain but is considerably diminished in glioblastoma… (More)
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2006
2006
Neuronal expression of keratinocyte-associated transmembrane protein-4, KCT-4, in mouse brain and its up-regulation by neurite outgrowth of Neuro-2a cells.
One group of proteins that regulates neurite outgrowth and maintains neuronal networks is the immunoglobulin superfamily (IgSF… (More)
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2003
2003
EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells.
Several tetraspanins bind directly to a few molecular partners to form primary complexes, which might assemble through… (More)
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Highly Cited
2001
Highly Cited
2001
EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily.
A novel Ig superfamily protein, EWI-2, was co-purified with tetraspanin protein CD81 under relatively stringent Brij 96 detergent… (More)
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