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Imipenem and Cilastatin Sodium
Known as:
Imipenem-Cilastatin Sodium
, imipenem-cilastatin, sodium salt
, Imipenem/Cilastatin Sodium
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A parenteral antibiotic preparation containing imipenem and cilastatin sodium with bactericidal activity. Imipenem, a broad spectrum beta-lactam…
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Cilastatin / Imipenem
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Effects of Fosfomycin and Imipenem/ Cilastatin on Nephrotoxicity and Renal Excretion of Vancomycin in Rats
Tsutomu Nakamura
,
Y. Hashimoto
,
Toshiyuki Kokuryo
,
K. Inui
Pharmaceutical Research
1998
Corpus ID: 23927649
AbstractPurpose. The effects of fosfomycin and imipenem/cilastatin on the nephrotoxicity of vancomycin were studied in rats, and…
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1996
1996
Pharmacokinetics of Aztreonam and Imipenem in Critically Ill Patients with Pneumonia
D. McKindley
,
B. Boucher
,
M. Hess
,
M. Croce
,
T. Fabian
Pharmacotherapy
1996
Corpus ID: 25059821
Study Objective. To evaluate the pharmacokinetic profiles of aztreonam and imipenem in critically ill trauma patients with…
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1996
1996
A meta-analysis of clinical studies of imipenem-cilastatin for empirically treating febrile neutropenic patients.
N. B. Deaney
,
H. Tate
Journal of Antimicrobial Chemotherapy
1996
Corpus ID: 22789675
There are many clinical studies comparing antibiotic treatments, but the majority are too small to have sufficient power to be…
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1995
1995
Antimicrobial activity of SM-17466, a novel carbapenem antibiotic with potent activity against methicillin-resistant Staphylococcus aureus
Yoshihiro Sumita
,
H. Nouda
,
K. Kanazawa
,
M. Fukasawa
Antimicrobial Agents and Chemotherapy
1995
Corpus ID: 20211822
The in vitro and in vivo antibacterial activities of SM-17466, a new 1 beta-methyl carbapenem, were evaluated against a wide…
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1992
1992
Efficacy of two comparative antibiotic regimens in the treatment of serious intra-abdominal infections: results of a multicenter study.
F. Eckhauser
,
J. Knol
,
S. Raper
,
M. Mulholland
,
P. Helzerman
Clinical Therapeutics
1992
Corpus ID: 1142338
A multicenter, open-label randomized trial was conducted to evaluate the efficacy and tolerability of monotherapy with imipenem…
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1991
1991
Infections associated with biliary drainage procedures in patients with cancer.
Nancy Khardori
,
Edna Wong
,
C. Humberto Carrasco
,
Sidney Wallace
,
Y. Patt
,
G. Bodey
Reviews of Infectious Diseases
1991
Corpus ID: 21605369
A total of 170 therapeutic biliary drainage procedures were carried out in 90 patients with cancer over a 1-year period (January…
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Review
1991
Review
1991
Use of antimicrobial drugs in adults before and after removal of a restriction policy.
CJ Himmelberg
,
R. Pleasants
,
+4 authors
TL Morris
American journal of hospital pharmacy
1991
Corpus ID: 25093154
The effects on the quantity and quality of antimicrobial drug use of removing an antimicrobial restriction policy are reported…
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1989
1989
Ectoenzymes of the kidney microvillar membrane. Isolation and characterization of the amphipathic form of renal dipeptidase and hydrolysis of its glycosyl-phosphatidylinositol anchor by an activity…
N. Hooper
,
A. Turner
Biochemical Journal
1989
Corpus ID: 44312016
Renal dipeptidase (EC 3.4.13.11) has been solubilized from pig kidney microvillar membranes with n-octyl-beta-D-glucopyranoside…
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Highly Cited
1986
Highly Cited
1986
Imipenem-cilastatin as initial therapy for febrile cancer patients
G. Bodey
,
M. Alvarez
,
P. Jones
,
K. Rolston
,
L. Steelhammer
,
V. Fainstein
Antimicrobial Agents and Chemotherapy
1986
Corpus ID: 840026
Imipenem-cilastatin was used to treat 79 febrile episodes in 71 cancer patients, most of whom had neutropenia. The overall…
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1986
1986
Imipenem-cilastatin in the treatment of methicillin-sensitive and methicillin-resistant Staphylococcus aureus infections
Wiley Fan
,
R. D. Busto
,
+5 authors
L. Saravolatz
Antimicrobial Agents and Chemotherapy
1986
Corpus ID: 26548045
Imipenem-cilastatin was evaluated for efficacy and toxicity as an antistaphylococcal agent in 23 patients; 11 of these patients…
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