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Imipenem and Cilastatin Sodium

Known as: Imipenem-Cilastatin Sodium, imipenem-cilastatin, sodium salt, Imipenem/Cilastatin Sodium 
A parenteral antibiotic preparation containing imipenem and cilastatin sodium with bactericidal activity. Imipenem, a broad spectrum beta-lactam… 
National Institutes of Health

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Broader (1)

Cilastatin / Imipenem

Papers overview

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2009
2009
Assessment of an Alternative Meropenem Dosing Strategy Compared with Imipenem‐Cilastatin or Traditional Meropenem Dosing After Cefepime Failure or Intolerance in Adults with Neutropenic Fever
Study Objective. To compare clinical outcomes of patients receiving an alternative dosage of meropenem with those of patients… 
1997
1997
Pharmacokinetics of Imipenem and Cilastatin During Continuous Venovenous Hemodialysis in Patients Who Are Critically III
The objective of this study is to study the pharmacokinetics of imipenem–cilastatin in patients with anuria related to multiorgan… 
1996
1996
Pharmacokinetics of Aztreonam and Imipenem in Critically Ill Patients with Pneumonia
Study Objective. To evaluate the pharmacokinetic profiles of aztreonam and imipenem in critically ill trauma patients with… 
1996
1996
A meta-analysis of clinical studies of imipenem-cilastatin for empirically treating febrile neutropenic patients.
There are many clinical studies comparing antibiotic treatments, but the majority are too small to have sufficient power to be… 
1995
1995
Antimicrobial activity of SM-17466, a novel carbapenem antibiotic with potent activity against methicillin-resistant Staphylococcus aureus
The in vitro and in vivo antibacterial activities of SM-17466, a new 1 beta-methyl carbapenem, were evaluated against a wide… 
1991
1991
[Epidemic outbreak of methicillin-resistant Staphylococcus aureus in a general hospital. Preliminary report].
The incidence of MRSA infections in Spain had remained in a low level through the years, being MRSA usually less than 1.5% of all… 
1991
1991
Imipenem‐cilastatin for empirical therapy in neutropenic patients with fever: An open study in patients with hematologic malignancies
Abstract: In adult neutropenic patients with hematological malignancies, we explored imipenem‐cilastatin as empirical antibiotic… 
1989
1989
Ectoenzymes of the kidney microvillar membrane. Isolation and characterization of the amphipathic form of renal dipeptidase and hydrolysis of its glycosyl-phosphatidylinositol anchor by an activity…
Renal dipeptidase (EC 3.4.13.11) has been solubilized from pig kidney microvillar membranes with n-octyl-beta-D-glucopyranoside… 
Highly Cited
1986
Highly Cited
1986
Imipenem-cilastatin as initial therapy for febrile cancer patients
Imipenem-cilastatin was used to treat 79 febrile episodes in 71 cancer patients, most of whom had neutropenia. The overall… 
Review
1986
Review
1986
Imipenem-cilastatin: the first thienamycin antibiotic.
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