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Imipenem and Cilastatin Sodium

Known as: Imipenem-Cilastatin Sodium, imipenem-cilastatin, sodium salt, Imipenem/Cilastatin Sodium 
A parenteral antibiotic preparation containing imipenem and cilastatin sodium with bactericidal activity. Imipenem, a broad spectrum beta-lactam… 
National Institutes of Health

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Broader (1)

Cilastatin / Imipenem

Papers overview

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1998
1998
Effects of Fosfomycin and Imipenem/ Cilastatin on Nephrotoxicity and Renal Excretion of Vancomycin in Rats
AbstractPurpose. The effects of fosfomycin and imipenem/cilastatin on the nephrotoxicity of vancomycin were studied in rats, and… 
1996
1996
Pharmacokinetics of Aztreonam and Imipenem in Critically Ill Patients with Pneumonia
Study Objective. To evaluate the pharmacokinetic profiles of aztreonam and imipenem in critically ill trauma patients with… 
1996
1996
A meta-analysis of clinical studies of imipenem-cilastatin for empirically treating febrile neutropenic patients.
There are many clinical studies comparing antibiotic treatments, but the majority are too small to have sufficient power to be… 
1995
1995
Antimicrobial activity of SM-17466, a novel carbapenem antibiotic with potent activity against methicillin-resistant Staphylococcus aureus
The in vitro and in vivo antibacterial activities of SM-17466, a new 1 beta-methyl carbapenem, were evaluated against a wide… 
1992
1992
Efficacy of two comparative antibiotic regimens in the treatment of serious intra-abdominal infections: results of a multicenter study.
A multicenter, open-label randomized trial was conducted to evaluate the efficacy and tolerability of monotherapy with imipenem… 
1991
1991
Infections associated with biliary drainage procedures in patients with cancer.
A total of 170 therapeutic biliary drainage procedures were carried out in 90 patients with cancer over a 1-year period (January… 
Review
1991
Review
1991
Use of antimicrobial drugs in adults before and after removal of a restriction policy.
The effects on the quantity and quality of antimicrobial drug use of removing an antimicrobial restriction policy are reported… 
1989
1989
Ectoenzymes of the kidney microvillar membrane. Isolation and characterization of the amphipathic form of renal dipeptidase and hydrolysis of its glycosyl-phosphatidylinositol anchor by an activity…
Renal dipeptidase (EC 3.4.13.11) has been solubilized from pig kidney microvillar membranes with n-octyl-beta-D-glucopyranoside… 
Highly Cited
1986
Highly Cited
1986
Imipenem-cilastatin as initial therapy for febrile cancer patients
Imipenem-cilastatin was used to treat 79 febrile episodes in 71 cancer patients, most of whom had neutropenia. The overall… 
1986
1986
Imipenem-cilastatin in the treatment of methicillin-sensitive and methicillin-resistant Staphylococcus aureus infections
Imipenem-cilastatin was evaluated for efficacy and toxicity as an antistaphylococcal agent in 23 patients; 11 of these patients… 
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