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Imipenem and Cilastatin Sodium

Known as: Imipenem-Cilastatin Sodium, imipenem-cilastatin, sodium salt, Imipenem/Cilastatin Sodium 
A parenteral antibiotic preparation containing imipenem and cilastatin sodium with bactericidal activity. Imipenem, a broad spectrum beta-lactam… 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Cilastatin / Imipenem

Papers overview

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Highly Cited
2018
Highly Cited
2018
Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: a phase 2, randomised, double-blind, non-inferiority trial.
Highly Cited
2017
Highly Cited
2017
In Vitro Activity of Imipenem-Relebactam against Gram-Negative ESKAPE Pathogens Isolated by Clinical Laboratories in the United States in 2015 (Results from the SMART Global Surveillance Program)
ABSTRACT Relebactam (formerly MK-7655) is an inhibitor of class A and C β-lactamases, including Klebsiella pneumoniae… 
Highly Cited
2016
Highly Cited
2016
Phase 2, Dose-Ranging Study of Relebactam with Imipenem-Cilastatin in Subjects with Complicated Intra-abdominal Infection
ABSTRACT Relebactam (REL [MK-7655]) is a novel class A/C β-lactamase inhibitor intended for use with imipenem for the treatment… 
Review
2015
Review
2015
The β‐Lactams Strike Back: Ceftazidime‐Avibactam
Gram‐negative resistance has reached a crucial point, with emergence of pathogens resistant to most or all available antibiotics… 
Review
2013
Review
2013
New β‐lactam–β‐lactamase inhibitor combinations in clinical development
Tazobactam was the most recent β‐lactamase inhibitor to be approved in 1993. Since the approval of piperacillin–tazobactam, the… 
Review
2007
Review
2007
Brief Communication: Tolerability of Meropenem in Patients with IgE-Mediated Hypersensitivity to Penicillins
Context Frequent cross-reactions between penicillins and imipenem, the prototype carbopenem, may discourage use of other… 
Highly Cited
2000
Highly Cited
2000
Appropriate use of restricted antimicrobial agents in hospitals: the importance of empirical therapy and assisted re-evaluation.
We evaluated the appropriateness of use of restricted antimicrobial agents in the context of a newly implemented order form and… 
Review
1999
Review
1999
Infection-Control Measures Reduce Transmission of Vancomycin-Resistant Enterococci in an Endemic Setting
Shortly after the emergence of vancomycin resistance in enterococci, vancomycin-resistant enterococci (VRE) spread throughout the… 
Highly Cited
1994
Highly Cited
1994
Behavior of antibiotics during human necrotizing pancreatitis
The aim of the study was to verify whether antibiotics excreted by the normal pancreas are also excreted in human necrotizing… 
Highly Cited
1992
Highly Cited
1992
Guidelines for clinical care: anti-infective agents for intra-abdominal infection. A Surgical Infection Society policy statement.
Several antibiotics have been marketed for therapeutic use in intra-abdominal infection. Often, these agents do not provide a… 
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