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Ibrolipim

A lipoprotein lipase (LPL) activator with antihyperlipidemic activity. Activation of LDL by ibrolipim lowers plasma triglycerides, with a concomitant… Expand
National Institutes of Health

Papers overview

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2011
2011
BackgroundThe role of renal lipoprotein lipase (LPL) per se in kidney diseases is still controversial and obscure. The purpose of… Expand
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2011
2011
OBJECTIVE Endothelial dysfunction is a key event in the onset and progression of atherosclerosis associated with diabetes… Expand
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2010
2010
Aim:To determine the effects and potential mechanisms of ibrolipim on ATP-binding membrane cassette transporter A-1 (ABCA1) and… Expand
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2009
2009
SUMMARY This study evaluates the induction potency of new drug candidates on mRNA levels of CYP1A2 and CYP3A4 in primary cultures… Expand
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2006
2006
The mRNA levels of human cytochrome P450 (CYP)2Cs and CYP3As in primary cultures of freshly isolated human hepatocytes were… Expand
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2006
2006
  • S. Kano, M. Doi
  • Metabolism: clinical and experimental
  • 2006
  • Corpus ID: 24186455
The synthetic compound NO-1886 (ibrolipim, [4-(4-bromo-2-cyano-phenylcarbamoyl)-benzyl]-phosphonic acid diethyl ester, CAS 133208… Expand
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2005
2005
Although the lipoprotein lipase (LPL) activator NO-1886 shows antiobesity effects in high-fat-induced obese animals, the… Expand
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2004
2004
In the present study, the effects on expression of cytochrome P450 (CYP1A1, CYP1A2, CYP3A4 and CYP3A5), carboxylesterase (CES1… Expand
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2004
2004
The synthetic compound NO-1886 (ibrolipim) is a lipoprotein lipase activator that has been proven to be highly effective in… Expand
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2003
2003
The lipoprotein lipase (LPL) activator NO-1886 (ibrolipim) has been shown to have potential benefits for the treatment of obesity… Expand
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