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ISIS 3082

Known as: ISIS-3082, ISIS3082 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Oligodeoxyribonucleotides

Papers overview

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2005
2005
The ICAM-1 antisense oligonucleotide ISIS-3082 prevents the development of postoperative ileus in mice.
Intestinal manipulation (IM) during abdominal surgery triggers the influx of inflammatory cells, leading to postoperative ileus… Expand
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2001
2001
Delivery of cholesteryl-conjugated phosphorothioate oligodeoxynucleotides to Kupffer cells by lactosylated low-density lipoprotein.
The efficacy of antisense oligonucleotides depends on the ability to reach in vivo their target cells. We aim to develop… Expand
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2000
2000
Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation.
Several studies have shown improved efficacy of cholesteryl-conjugated phosphorothioate antisense oligodeoxynucleotides. To gain… Expand
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Highly Cited
1997
Highly Cited
1997
In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells.
Systemically administered phosphorothioate antisense oligodeoxynucleotides can specifically affect the expression of their target… Expand
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Highly Cited
1997
Highly Cited
1997
An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice.
Mice treated p.o. with 5% dextran sodium sulfate develop a mild to moderate colitis characterized by focal areas of inflammation… Expand
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