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ISG15 gene

Known as: ISG15, ISG15 ubiquitin-like modifier, UBIQUITIN-LIKE MODIFIER ISG15 
This gene is involved in both protein tagging and cell signaling.
National Institutes of Health

Related topics

Related topics

2 relations
Signal TransductionUbiquitin-Like Protein ISG15

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Interferon‐stimulated gene 15 promotes cholesterol efflux by activating autophagy via the miR‐17‐5p/Beclin‐1 pathway in THP‐1 macrophage‐derived foam cells
2017
2017
ISG15 silencing increases cisplatin resistance via activating p53-mediated cell DNA repair
Tumor cells frequently evolved resistance to cisplatin that greatly compromises the efficacy of chemotherapy. Identification of… 
2013
2013
UBP 43 is a novel regulator of interferon signaling independent of its ISG 15 isopeptidase activity
Oxana A Malakhova, Keun Il Kim, Jiann-Kae Luo, Weiguo Zou, KG Suresh Kumar, Serge Y Fuchs, Ke Shuai and Dong-Er Zhang* Department… 
Review
2013
Review
2013
The ubiquitin-like protein Smt 3 p is activated for conjugation to other proteins by an Aos 1 p / Uba 2 p heterodimer mere-binding protein ( Meluh and Koshland , 1995 ) . Smt 3 p
mere-binding protein (Meluh and Koshland, 1995). Smt3p Erica S.Johnson1, Ingrid Schwienhorst2, is 48% identical to SUMO-1 and 17… 
2012
2012
ISG15 Deregulates Autophagy in Genotoxin-treated Ataxia Telangiectasia Cells*
Background: Aberrant activation of autophagy (proteinopathy) leads to neurodegeneration in various neurological disorders… 
2011
2011
ISG15 Modulates Development of the Erythroid Lineage
Activation of erythropoietin receptor allows erythroblasts to generate erythrocytes. In a search for genes that are up-regulated… 
2010
2010
Anchors Away for Ubiquitin Chains
Unanchored chains of ubiquitin molecules control a cell signaling pathway that responds to viral infection. It has become… 
Highly Cited
2008
Highly Cited
2008
UBE1L causes lung cancer growth suppression by targeting cyclin D1
UBE1L is the E1-like ubiquitin-activating enzyme for the IFN-stimulated gene, 15-kDa protein (ISG15). The UBE1L-ISG15 pathway was… 
Review
2003
Review
2003
ISG15, not just another ubiquitin-like protein.
Highly Cited
1992
Highly Cited
1992
Mx genes show weaker primary response to virus than other interferon-regulated genes.
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