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IS 741

Known as: IS-741 
National Institutes of Health

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1 relation

Broader (1)

Pyridines

Papers overview

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2007
2007
IS-741 Attenuates Local Migration of Monocytes and Subsequent Pancreatic Fibrosis in Experimental Chronic Pancreatitis Induced by Dibutyltin Dichloride in Rats
Objectives: Chronic pancreatitis consists of excessive leukocyte infiltration and fibrosis. IS-741 has been reported to be an… 
2004
2004
Effect of Carboxamide Derivative IS-741 on Rat Spontaneous Chronic Pancreatitis
This study aimed to analyze the therapeutic effects of the carboxamide derivative IS-741 on spontaneous chronic pancreatitis (CP… 
2001
2001
Efficacy of the inflammatory cell infiltration inhibitor IS-741 on colitis induced by dextran sulfate sodium in the rat.
We examined the therapeutic effects of the inflammatory cell infiltration inhibitor IS-741 (N-(2-((ethylsulfonyl)amino)-5… 
1999
1999
Effect of IS-741 (A New Synthetic Antiinflammatory Agent) on Acute Necrotizing Pancreatitis in Dogs
IS-741, a new synthetic anti-inflammatory agent, is known to have some inhibitory effect on cytosolic phospholipase A2 (cPLA2… 
1999
1999
A Novel Synthetic Anti-Acute Pancreatitis Agent, IS-741
A novel synthetic drug, IS-741, inhibited cell adhesion in vitro and neutrophil in vivo. Thus, IS-741 inhibited the magnification… 
1999
1999
The Novel Carboxamide Derivative IS-741 Reduces Neutrophil Chemoattractant Production by Bronchoalveolar Macrophages in Rats with Cerulein-Induced Pancreatitis Complicated by Sepsis
Background/Aims: The priming mechanism of macrophages to secrete cytokines in acute pancreatitis is important for remote organ… 
1999
1999
Effect of IS-741 on cell adhesion between human umbilical vein endothelial cells and HL-60 cells.
The effect of IS-741 (N-[(2-ethylsulfonylamino)-5-trifluoromethyl-3-pyridyl] cyclohexanecarboxamide monohydrate) on a model for… 
1999
1999
Novel Carboxamide Derivative (IS-741) Attenuates Lung Injury in Rats with Cerulein-Induced Pancreatitis Complicated by Endotoxemia
The therapeutic effects of an intravenouslyinjected carboxamide derivative (IS-741) on lung injurywere studied in rats with… 
1999
1999
A Novel Diamino-Pyridine Derivative Prevents Excessive Leukocyte Infiltration in Aggravation of Acute Necrotizing Pancreatitis
Leukocyte infiltration in the pancreas is involved in the aggravation of acute pancreatitis from edematous phase into necrotic… 
1995
1995
Synthesis and antipancreatitis activities of novel N-(2-sulfonylamino-5-trifluoromethyl-3-pyridyl)carboxamide derivatives as phospholipase A2 inhibitors.
Novel N-(2-sulfonylamino-5-trifluoromethyl-3-pyridyl)carboxamide derivatives have been prepared and evaluated as phospholipase A2… 
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