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IS 741

Known as: IS-741 
National Institutes of Health

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1 relation

Broader (1)

Pyridines

Papers overview

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2009
2009
Effects of IS-741, a Synthetic Anti-Inflammatory Agent, on Bleomycin-Induced Lung Injury in Mice
Bleomycin (BLM)-induced lung injury consists of excessive inflammatory cell infiltration and fibrosis. IS-741 has been reported… 
2007
2007
IS-741 Attenuates Local Migration of Monocytes and Subsequent Pancreatic Fibrosis in Experimental Chronic Pancreatitis Induced by Dibutyltin Dichloride in Rats
Objectives: Chronic pancreatitis consists of excessive leukocyte infiltration and fibrosis. IS-741 has been reported to be an… 
2004
2004
Effect of Carboxamide Derivative IS-741 on Rat Spontaneous Chronic Pancreatitis
This study aimed to analyze the therapeutic effects of the carboxamide derivative IS-741 on spontaneous chronic pancreatitis (CP… 
2002
2002
Inhibitory effects of the new anti‐inflammatory agent, IS‐741, on spontaneous colitis in HLA‐B27/β2‐microglobulin transgenic rats
Abstract Background: A novel anti‐inflammatory drug, IS‐741, blocked the adhesion of inflammatory cells to microvascular… 
2001
2001
Efficacy of the inflammatory cell infiltration inhibitor IS-741 on colitis induced by dextran sulfate sodium in the rat.
We examined the therapeutic effects of the inflammatory cell infiltration inhibitor IS-741 (N-(2-((ethylsulfonyl)amino)-5… 
1999
1999
Effect of IS-741 (A New Synthetic Antiinflammatory Agent) on Acute Necrotizing Pancreatitis in Dogs
IS-741, a new synthetic anti-inflammatory agent, is known to have some inhibitory effect on cytosolic phospholipase A2 (cPLA2… 
1999
1999
A Novel Synthetic Anti-Acute Pancreatitis Agent, IS-741
A novel synthetic drug, IS-741, inhibited cell adhesion in vitro and neutrophil in vivo. Thus, IS-741 inhibited the magnification… 
1999
1999
The Novel Carboxamide Derivative IS-741 Reduces Neutrophil Chemoattractant Production by Bronchoalveolar Macrophages in Rats with Cerulein-Induced Pancreatitis Complicated by Sepsis
Background/Aims: The priming mechanism of macrophages to secrete cytokines in acute pancreatitis is important for remote organ… 
1999
1999
Novel Carboxamide Derivative (IS-741) Attenuates Lung Injury in Rats with Cerulein-Induced Pancreatitis Complicated by Endotoxemia
The therapeutic effects of an intravenouslyinjected carboxamide derivative (IS-741) on lung injurywere studied in rats with… 
1995
1995
Synthesis and antipancreatitis activities of novel N-(2-sulfonylamino-5-trifluoromethyl-3-pyridyl)carboxamide derivatives as phospholipase A2 inhibitors.
Novel N-(2-sulfonylamino-5-trifluoromethyl-3-pyridyl)carboxamide derivatives have been prepared and evaluated as phospholipase A2… 
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