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IPI-926
Known as:
FIN-5
, IP9 Free Base
, Smoothened Antagonist IPI-926
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National Institutes of Health
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Related topics
Related topics
2 relations
Broader (1)
Veratrum Alkaloids
Narrower (1)
saridegib
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Targeted therapies for medulloblastoma: understanding the mechanisms of drug resistance and exploring new peptide-based therapeutics
M. Lee
2013
Corpus ID: 71054175
Medulloblastoma, the most common malignant pediatric brain tumor, is currently treated with nonspecific cytotoxic therapies…
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2012
2012
Abstract 979: The anti-tumor activity of the Smoothened inhibitor IPI-926 in models of residual disease is time dependent
E. Mandley
,
V. Campbell
,
+5 authors
C. Fritz
2012
Corpus ID: 72327047
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Although response rates can be high for some solid…
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2012
2012
Abstract 3285: Hedgehog pathway inhibition delays regrowth of ovarian cancer following paclitaxel and carboplatinum only if initiated immediately after completion of chemotherapy
Kashmira Kulkarni‐Datar
,
W. Growdon
,
Jeanne A. Ferguson
,
J. Macdougall
,
R. Foster
,
B. Rueda
2012
Corpus ID: 75818821
The high mortality associated with ovarian cancer is attributed to the lack of any reliable early detection method, unknown…
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2010
2010
Abstract 5045: The Hh inhibitor IPI-926 inhibits relapse of a non-small cell lung cancer xenograft model following treatment with an EGF-R targeted tyrosine kinase inhibitor
E. Mandley
,
Kerry F White
,
+4 authors
J. Macdougall
2010
Corpus ID: 71448465
The Hedgehog (Hh) pathway plays a key role in multiple types of cancer, either by mutational activation of the pathway in tumor…
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2010
2010
Abstract LB-374: The Hh inhibitor IPI-926 enhances tumor perfusion and nab-paclitaxel activity in a pancreatic xenograft model
Veronica Travaglione
,
I. Deyneko
,
+5 authors
J. Macdougall
2010
Corpus ID: 75742389
Malignant activation of the Hedgehog (Hh) pathway is associated with multiple tumor types. In certain cancers, such as pancreatic…
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2010
2010
Formulations orales d'inhibiteur de la voie hedgehog
Bennett Carter
,
John J. Lee
,
Hanan Sheikh
2010
Corpus ID: 193046927
L'invention concerne des formulations orales du produit medicamenteux IPI-926. L'invention concerne egalement des formulations…
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2010
2010
Significance of the hedgehog (Hh) pathway in ovarian cancer xenograft growth.
B. Rueda
,
C. McCann
,
+5 authors
J. Macdougall
2010
Corpus ID: 79385565
5058 Background: Initial immunohistochemical analysis revealed that about 50% of ovarian cancer samples expressed sonic Hh ligand…
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2008
2008
Depilation induced anagen as a model to study hedgehog pathway antagonist IPI-926: Implications for biomarker development
K. Faia
,
E. Mandley
,
+9 authors
Karen McGovern
2008
Corpus ID: 81488509
2827 The Hedgehog cell signaling pathway is normally active during embryonic development and plays a critical role in controlling…
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