INCB7839
National Institutes of Health
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High-grade gliomas (HGGs) are the most lethal type of brain tumour in both children and adults. The heterogeneous nature of these…
Background: Inhibitors of HER-2/neu and EGF receptors such as trastuzumab, lapatinib, and erlotinib have demonstrated clinical…
The HER-2 receptor tyrosine kinase is an important regulator of cell proliferation and survival, and it is a clinically validated…