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INCB028050

Known as: INCB 028050 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

baricitinib

Papers overview

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Highly Cited
2014
Highly Cited
2014
The pharmacokinetics, pharmacodynamics, and safety of baricitinib, an oral JAK 1/2 inhibitor, in healthy volunteers.
Baricitinib (also known as LY3009104 or INCB028050), a novel and potent small molecule inhibitor of Janus kinase family of… Expand
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2013
2013
LB0005 12-week results of a phase 2B dose-ranging study of LY3009104 (INCB028050), an oral JAK1/JAK2 inhibitor, in combination with traditional dmards in patients with rheumatoid arthritis
Background LY3009104 (LY) is a novel, oral inhibitor of the JAK1/JAK2 signalling pathway known to be important in the… Expand
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2013
2013
Inhibition of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signalling pathway in rheumatoid synovial fibroblasts using small molecule compounds.
Janus kinase (JAK) inhibitors have been developed as anti-inflammatory agents and have demonstrated clinical efficacy in… Expand
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Review
2013
Review
2013
SP0169 JAK inhibition in patients with rheumatoid arthritis
The Janus Kinase (JAK) group of tyrosine kinases are intracellular signaling molecules which become phosphorylated upon… Expand
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2012
2012
F1000Prime recommendation of A Randomized Dose-Ranging, Placebo-Controlled Study of INCB028050, a Selective JAK1 and JAK2 Inhibitor in Subjects with Active Rheumatoid Arthritis.
 
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Highly Cited
2010
Highly Cited
2010
Selective Inhibition of JAK1 and JAK2 Is Efficacious in Rodent Models of Arthritis: Preclinical Characterization of INCB028050
Inhibiting signal transduction induced by inflammatory cytokines offers a new approach for the treatment of autoimmune diseases… Expand
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2010
2010
Selective Inhibition of JAK 1 and JAK 2 Is Efficacious in Rodent Models of Arthritis : Preclinical Characterization of INCB 028050
 
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2010
2010
Preclinical Characterization of INCB 028050 Efficacious in Rodent Models of Arthritis : Selective Inhibition of JAK 1 and JAK 2 Is
 
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2010
2010
Are Th 17 Cells an Appropriate New Target in the Treatment of Rheumatoid Arthritis ?
Discovery of Th 17 cells Until about a decade ago, many human autoimmune diseases and the corresponding experimental animal… Expand
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