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IIK7

National Institutes of Health

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Papers overview

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2017
2017
Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas/FasL-caspase-3
Purpose Previous studies have shown that melatonin (MEL) signaling is involved in the modulation of photoreceptor viability… 
2016
2016
Melatonin modulates the functions of porcine granulosa cells via its membrane receptor MT2 in vitro.
2015
2015
Effect of Melatonin and Analogues on Corneal Wound Healing: Involvement of Mt2 Melatonin Receptor
Abstract Purpose: We have investigated the effect of melatonin and its analogues on rabbit corneal epithelial wound healing… 
2015
2015
Melatonin Entrains PER2::LUC Bioluminescence Circadian Rhythm in the Mouse Cornea.
PURPOSE Previous studies have reported the presence of a circadian rhythm in PERIOD2::LUCIFERASE (PER2::LUC) bioluminescence in… 
2013
2013
Melatonin receptor agonist-induced reduction of SNP-released nitric oxide and cGMP production in isolated human non-pigmented ciliary epithelial cells.
2013
2013
Characterization of signaling pathways coupled to melatonin receptors in gastrointestinal smooth muscle
Review
2011
Review
2011
Melatonin Receptor Agonists: New Options for Insomnia and Depression Treatment
The circadian nature of melatonin (MLT) secretion, coupled with the localization of MLT receptors to the suprachiasmatic nucleus… 
2009
2009
Sleep-promoting action of IIK7, a selective MT2 melatonin receptor agonist in the rat
2008
2008
Sympathetic nervous system modulates the ocular hypotensive action of MT2‐melatonin receptors in normotensive rabbits
Abstract:  The aim of this study was to investigate the hypotensive effect of the melatonin analogue, N‐butanoyl‐2‐(2‐methoxy‐6H… 
1999
1999
Design of subtype selective melatonin receptor agonists and antagonists.
Studies of the physiological actions of melatonin have been hindered by the lack of specific, potent and subtype selective… 
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