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IGL gene

Known as: Immunoglobulin Lambda Locus, Lambda Light Chain Gene, IGL 
This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant… 
National Institutes of Health

Related topics

Related topics

4 relations
22q11.1-q11.2Humoral ImmunityImmune responseImmunoglobulin lambda-Chains

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Ehrlichia chaffeensis TRP120 Interacts with a Diverse Array of Eukaryotic Proteins Involved in Transcription, Signaling, and Cytoskeleton Organization
ABSTRACT Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes and… 
Highly Cited
1999
Highly Cited
1999
Protein Displays of the Human Immunoglobulin Heavy, Kappa and Lambda Variable and Joining Regions
‘Protein displays of the Human Immunoglobulin Heavy, Kappa and Lambda Variable and Joining Regions’, the 6th report of the ‘IMGT… 
1999
1999
Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vlambda repertoire.
The expressed human immunoglobulin Vlambda repertoire demonstrates a strong bias in the use of individual Vlambda segments… 
1997
1997
Diffuse large cell, B-cell type lymphoma with a novel translocation (2;22)(p23;q11.2).
1997
1997
Chromosomal location of the human immunoglobulin lambda variable 8 (IGLV8) gene family outside the major lambda locus on chromosome 22q11.2.
1993
1993
Long-range restriction map of human chromosome 22q11-22q12 between the lambda immunoglobulin locus and the Ewing sarcoma breakpoint.
A long-range restriction map of the region between the immunoglobulin lambda locus and the Ewing sarcoma breakpoint has been… 
1992
1992
Absence of immunoglobulin variable region hypermutation in a large cell lymphoma after in vivo and in vitro propagation.
Several genetic mechanisms have been shown to diversity the expressed antibody repertoire of committed B lymphocytes. These… 
Highly Cited
1990
Highly Cited
1990
A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.
As a first step toward defining the elements necessary for lambda immunoglobulin gene regulation, DNase I hypersensitive sites… 
1990
1990
Enhancer sequences located 3' of the mouse immunoglobulin lambda locus specify high-level expression of an immunoglobulin lambda gene in B cells of transgenic mice.
In contrast to the mouse immunoglobulin heavy chain and kappa light chain genes, very little is known about the regulation of… 
1983
1983
Primary structure of the variable region of a human lambda VI light chain: Bence Jones protein SUT.
To ascertain if lambda VI light chains have unique structural features that account for the preferential association of these… 
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