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IGF2 wt Allele

Known as: PP9974, Insulin-Like Growth Factor 2 (Somatomedin A) wt Allele, IGF-II 
Human IGF2 wild-type allele is located in the vicinity of 11p15.5 and is approximately 15 kb in length. This allele, which encodes insulin-like… 
National Institutes of Health

Related topics

Related topics

8 relations
11p15.5Cell Proliferation Regulatory ProcessHomo sapiensIntercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
[Exceptionally high content of mRNA of IGF-II-associated protein in meningiomas].
A comparison of gene expression profiles in different types of human brain tumours and normal brain by Serial Analysis of Gene… 
2005
2005
IGF-II mRNA and protein are expressed in the stroma of invasive breast cancers: Anin situ hybridization and immunohistochemistry study
Insulin-like growth factor-II (IGF-II) is a potent mitogen for a variety of cell types and is considered an important regulator… 
Highly Cited
2005
Highly Cited
2005
Expression and alteration of insulin-like growth factor II-messenger RNA in hepatoma tissues and peripheral blood of patients with hepatocellular carcinoma.
AIM To investigate the clinical values of serum free insulin-like growth factor II (IGF-II) levels and IGF-II mRNA in… 
1999
1999
Hammerhead ribozyme-mediated cleavage of the human insulin-like growth factor-II ribonucleic acid in vitro and in prostate cancer cells.
Insulin-like growth factor (IGF)-II plays an important role in fetal growth and development. IGFs are potent mitogens for a… 
1995
1995
The Human Insulin-Like Growth Factor-II Promoter P1 is not Restricted to Liver: Evidence for Expression of P1 in other Tissues and for a Homologous Promoter in Baboon Liver
The human insulin-like growth factor (IGF)-II gene (IGF2) contains 4 different promoters (P1-P4), three of which (P2-P4) are… 
1993
1993
Effect of endocrine therapy on growth of T61 human breast cancer xenografts is directly correlated to a specific down-regulation of insulin-like growth factor II (IGF-II).
1992
1992
Isolation of an insulin-like growth factor II cDNA from guinea pig liver: Expression and developmental regulation
1990
1990
A simple and efficient scheme for the purification of insulin-like growth factor II from human bone matrix extract.
Human insulin-like growth factor II (IGF-II) has been purified to homogeneity from bone which contained 10-15 times more IGF-II… 
Highly Cited
1990
Highly Cited
1990
Growth hormone mediates the growth of T-lymphoblast cell lines via locally generated insulin-like growth factor-I.
It has become evident that locally produced insulin-like growth factors-I and -II (IGF-I and IGF-II) play an important role in… 
Highly Cited
1987
Highly Cited
1987
Interactions of the receptor for insulin-like growth factor II with mannose-6-phosphate and antibodies to the mannose-6-phosphate receptor.
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