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IDN 1965
Known as:
IDN-1965
, IDN1965
National Institutes of Health
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Review
2017
Review
2017
Pyrrolizidine alkaloids enhance alcohol-induced hepatocytotoxicity in vitro in normal human hepatocytes.
M. Neuman
,
L. Cohen
,
V. Steenkamp
European Review for Medical and Pharmacological…
2017
Corpus ID: 4047876
OBJECTIVE Herbal remedies containing pyrrilidozine alkaloids (PA)s can induce liver damage, including hepato-sinusoidal…
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Highly Cited
2003
Highly Cited
2003
The caspase inhibitor IDN‐6556 prevents caspase activation and apoptosis in sinusoidal endothelial cells during liver preservation injury
S. Natori
,
H. Higuchi
,
P. Contreras
,
G. Gores
Liver transplantation
2003
Corpus ID: 20129428
Cold ischemia (CI)–warm reperfusion (WR) liver injury remains a problem in liver transplantation. CI‐WR initially causes…
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Highly Cited
2003
Highly Cited
2003
Inhibition of Cardiac Myocyte Apoptosis Improves Cardiac Function and Abolishes Mortality in the Peripartum Cardiomyopathy of G&agr;q Transgenic Mice
Y. Hayakawa
,
M. Chandra
,
+5 authors
R. Kitsis
Circulation
2003
Corpus ID: 20731044
Background—Although the occurrence of cardiac myocyte apoptosis during heart failure has been documented, its importance in…
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2003
2003
Apoptotic Cell Death and Function of Cryopreserved Porcine Hepatocytes in a Bioartificial Liver
T. Matsushita
,
T. Yagi
,
+5 authors
S. Nyberg
Cell Transplantation
2003
Corpus ID: 9230887
We have previously shown that cryopreservation leads to increased apoptotic death of porcine hepatocytes intended for use in a…
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2001
2001
Inhibition of caspases in vivo protects the rat liver against alcohol-induced sensitization to bacterial lipopolysaccharide.
I. Deaciuc
,
N. D'souza
,
+4 authors
C. McClain
Alcoholism: Clinical and Experimental Research
2001
Corpus ID: 20516698
BACKGROUND The mechanisms of liver sensitization by alcohol to Gram-negative bacterial lipopolysaccharide (LPS) remain elusive…
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2001
2001
Characterization of the caspase inhibitor IDN-1965 in a model of apoptosis-associated liver injury.
N. Hoglen
,
B. Hirakawa
,
+8 authors
P. Contreras
Journal of Pharmacology and Experimental…
2001
Corpus ID: 19793287
Previous studies have shown that caspase inhibitors are effective at protecting against anti-Fas antibody (alpha-Fas)-mediated…
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Highly Cited
1999
Highly Cited
1999
Apoptosis of sinusoidal endothelial cells occurs during liver preservation injury by a caspase-dependent mechanism.
S. Natori
,
M. Selzner
,
+4 authors
G. Gores
Transplantation
1999
Corpus ID: 29045911
BACKGROUND Cold ischemia/warm reperfusion (CI/WR) liver injury remains a problem in liver transplants. Sinusoidal endothelial…
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