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ICMT gene

Known as: ICMT, PPMT, PRENYLCYSTEINE CARBOXYLMETHYLTRANSFERASE 
National Institutes of Health

Related topics

Related topics

1 relation
protein-S-isoprenylcysteine O-methyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Inhibition of isoprenylcysteine carboxylmethyltransferase sensitizes common chemotherapies in cervical cancer via Ras-dependent pathway.
2018
2018
Isoprenylcysteine carboxylmethyltransferase regulates ovarian cancer cell response to chemotherapy and Ras activation.
2017
2017
Inhibiting prenylation augments chemotherapy efficacy in renal cell carcinoma through dual inhibition on mitochondrial respiration and glycolysis.
2016
2016
Icmt inhibition exerts anti-angiogenic and anti-hyperpermeability activities impeding malignant pleural effusion
Small GTPases are pivotal regulators of several aspects of tumor progression. Their implication in angiogenesis, vascular… 
2012
2012
Inhibitors of protein geranylgeranyltransferase-I lead to prelamin A accumulation in cells by inhibiting ZMPSTE24
Protein farnesyltransferase (FTase) inhibitors, generally called “FTIs,” block the farnesylation of prelamin A, inhibiting the… 
2009
2009
Enzymatic methyl esterification of a deamidated form of mouse epidermal growth factor.
The enzyme S-adenosylmethionine:protein carboxyl-O-methyl-transferase, type II (EC 2.1.1.77; PCMT) from eukaryotes methyl… 
Highly Cited
2008
Highly Cited
2008
Inactivating Icmt ameliorates K-RAS-induced myeloproliferative disease.
Hyperactive signaling through the RAS proteins is involved in the pathogenesis of many forms of cancer. The RAS proteins and many… 
2007
2007
Cox-2 promotes chromogranin A expression and bioactivity: evidence for a prostaglandin E2-dependent mechanism and the involvement of a proximal cyclic adenosine 5'-monophosphate-responsive element.
The prostanoid biosynthetic enzyme cyclooxygenase-2 (Cox-2) is up-regulated in several neuroendocrine tumors. The aim of the… 
1991
1991
Inhibition of adsorption of oral streptococci to saliva treated hydroxyapatite by chitin derivatives.
This study estimated the effects of five chitin derivatives low molecular chitosan (LMCS), ethyleneglycol chitin (PEGT… 
Review
1988
Review
1988
Modification of isoaspartyl peptides and proteins by protein carboxyl methyltransferase from bovine brain.
Recent findings indicate that protein carboxyl methyltransfer-ases (PCMTs) from mammalian brain and erythrocytes selectively and… 
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