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ICA105574

 
National Institutes of Health

Papers overview

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2020
2020
Toward a Structural View of hERG Activation by the Small-Molecule Activator ICA-105574
Outward current conducted by human ether-à-go-go-related gene type 1 (hERG1) K+ channels is important for action potential… Expand
2012
2012
Tuning of EAG K+ channel inactivation: Molecular determinants of amplification by mutations and a small molecule
Ether-à-go-go (EAG) and EAG-related gene (ERG) K+ channels are close homologues but differ markedly in their gating properties… Expand
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2011
2011
Molecular Determinants for Activation of Human Ether-à-go-go-related Gene 1 Potassium Channels by 3-Nitro-N-(4-phenoxyphenyl) Benzamide
Human ether-à-go-go-related gene 1 (hERG1) channels mediate repolarization of cardiac action potentials. Inherited long QT… Expand
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