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IC 87201

Known as: IC-87201, IC87201 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2015
012320092015

Papers overview

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2016
2016
Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein-protein interaction inhibitors.
Limitations of preclinical models of human memory contribute to the pervasive view that rodent models do not adequately predict… (More)
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2015
2015
Biochemical investigations of the mechanism of action of small molecules ZL006 and IC87201 as potential inhibitors of the nNOS-PDZ/PSD-95-PDZ interactions
ZL006 and IC87201 have been presented as efficient inhibitors of the nNOS/PSD-95 protein-protein interaction and shown great… (More)
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2015
2015
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
Aberrant increases in NMDA receptor (NMDAR) signaling contributes to central nervous system sensitization and chronic pain by… (More)
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2015
2015
Small-molecule inhibitors at the PSD-95/nNOS interface protect against glutamate-induced neuronal atrophy in primary cortical neurons.
Glutamate and nitric oxide (NO) are important regulators of dendrite and axon development in the central nervous system. Excess… (More)
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2014
2014
Small-molecule inhibitors at the PSD-95/nNOS interface attenuate MPP+-induced neuronal injury through Sirt3 mediated inhibition of mitochondrial dysfunction.
Post-synaptic density protein 95 (PSD-95) links neuronal nitric oxide synthase (nNOS) with the N-methyl-D-aspartic acid (NMDA… (More)
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2013
2013
Small-Molecule Inhibitors at the PSD-95/nNOS Interface have Antidepressant-Like Properties in Mice
Previous studies have demonstrated that nitric oxide (NO) synthase inhibitors are as efficacious as tricyclic antidepressants in… (More)
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2009
2009
Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents.
BACKGROUND AND PURPOSE Post-synaptic density protein 95 (PSD95) contains three PSD95/Dosophilia disc large/ZO-1 homology domains… (More)
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