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Hypoxia
Known as:
Hypoxic
, Oxygen Deficiency
, Deficiency, Oxygen
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A condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the…
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National Institutes of Health
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Related topics
Related topics
32 relations
Altitude Sickness
Asphyxia
Atmospheric Pressure
Brain Hypoxia
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Narrower (4)
Anoxemia
Myocardial Ischemia
neonatal hypoxia
vascular ischemia
Broader (5)
Anoxia
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock 2012
R. Dellinger
,
M. Levy
,
+20 authors
R. Moreno
Critical care medicine
2013
Corpus ID: 34855187
Objective:To provide an update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock…
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Highly Cited
2012
Highly Cited
2012
Acute respiratory distress syndrome: the Berlin Definition.
V. Ranieri
,
G. Rubenfeld
,
+5 authors
Arthur S Slutsky
JAMA
2012
Corpus ID: 36276275
The acute respiratory distress syndrome (ARDS) was defined in 1994 by the American-European Consensus Conference (AECC); since…
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Highly Cited
2012
Highly Cited
2012
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012
R. Dellinger
,
M. Levy
,
+20 authors
R. Moreno
Intensive Care Medicine
2012
Corpus ID: 8343565
ObjectiveTo provide an update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock…
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Review
2005
Review
2005
Porosity of 3D biomaterial scaffolds and osteogenesis.
V. Karageorgiou
,
D. Kaplan
Biomaterials
2005
Corpus ID: 31593209
Highly Cited
2000
Highly Cited
2000
Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia-inducible Factor-1α during Hypoxia
N. Chandel
,
D. S. McClintock
,
+4 authors
P. Schumacker
The Journal of Biological Chemistry
2000
Corpus ID: 31234413
During hypoxia, hypoxia-inducible factor-1α (HIF-1α) is required for induction of a variety of genes including erythropoietin and…
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Highly Cited
1996
Highly Cited
1996
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
J. Forsythe
,
B. Jiang
,
+4 authors
G. Semenza
Molecular and cellular biology
1996
Corpus ID: 6345452
Expression of vascular endothelial growth factor (VEGF) is induced in cells exposed to hypoxia or ischemia. Neovascularization…
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Highly Cited
1995
Highly Cited
1995
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
G. Wang
,
B. Jiang
,
E. Rue
,
G. Semenza
Proceedings of the National Academy of Sciences…
1995
Corpus ID: 26434952
Hypoxia-inducible factor 1 (HIF-1) is found in mammalian cells cultured under reduced O2 tension and is necessary for…
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Highly Cited
1995
Highly Cited
1995
Purification and Characterization of Hypoxia-inducible Factor 1 (*)
Guang-lan Wang
,
G. Semenza
The Journal of Biological Chemistry
1995
Corpus ID: 41659164
Hypoxia-inducible factor 1 (HIF-1) is a DNA-binding protein that activates erythropoietin (Epo) gene transcription in Hep3B cells…
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Review
1994
Review
1994
The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.
G. Bernard
,
A. Artigas
,
+7 authors
R. Spragg
American journal of respiratory and critical care…
1994
Corpus ID: 28302335
The acute respiratory distress syndrome (ARDS), a process of nonhydrostatic pulmonary edema and hypoxemia associated with a…
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Highly Cited
1992
Highly Cited
1992
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
D. Shweiki
,
A. Itin
,
D. Soffer
,
E. Keshet
Nature
1992
Corpus ID: 4366410
INEFFICIENT vascular supply and the resultant reduction in tissue oxygen tension often lead to neovascularization in order to…
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