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Hypoxia
Known as:
Hypoxic
, Oxygen Deficiency
, Deficiency, Oxygen
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A condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the…
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National Institutes of Health
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Related topics
Related topics
32 relations
Altitude Sickness
Asphyxia
Atmospheric Pressure
Brain Hypoxia
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Narrower (4)
Anoxemia
Myocardial Ischemia
neonatal hypoxia
vascular ischemia
Broader (5)
Anoxia
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
MiRNA-Directed Regulation of VEGF and Other Angiogenic Factors under Hypoxia
Zhong Hua
,
Q. Lv
,
+8 authors
Yaou Zhang
PLoS ONE
2006
Corpus ID: 2437922
MicroRNAs (miRNAs) are a class of 20–24 nt non-coding RNAs that regulate gene expression primarily through post-transcriptional…
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Review
2001
Review
2001
Interleukin-8 and human cancer biology.
K. Xie
Cytokine & growth factor reviews
2001
Corpus ID: 39547347
Highly Cited
2001
Highly Cited
2001
Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression*
Lawrence B. Gardner
,
Qing Li
,
Michele S. Park
,
W. Flanagan
,
G. Semenza
,
C. Dang
Journal of Biological Chemistry
2001
Corpus ID: 22769747
Mammalian cellular responses to hypoxia include adaptive metabolic changes and a G1 cell cycle arrest. Although transcriptional…
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Highly Cited
1998
Highly Cited
1998
Stabilization of wild-type p53 by hypoxia-inducible factor 1α
W. An
,
M. Kanekal
,
M. Simon
,
E. Maltepe
,
M. Blagosklonny
,
L. Neckers
Nature
1998
Corpus ID: 4423081
Although hypoxia (lack of oxygen in body tissues) is perhaps the most physiological inducer of the wild-type p53 gene, the…
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Highly Cited
1998
Highly Cited
1998
Reactive Oxygen Species Released from Mitochondria during Brief Hypoxia Induce Preconditioning in Cardiomyocytes*
T. V. Vanden Hoek
,
L. Becker
,
Z. Shao
,
Changqing Li
,
P. Schumacker
Journal of Biological Chemistry
1998
Corpus ID: 23370055
Reactive oxygen species (ROS) have been proposed to participate in the induction of cardiac preconditioning. However, their…
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Review
1998
Review
1998
Signaling to p53 Breaking the MDM2–p53 Circuit
C. Prives
Cell
1998
Corpus ID: 15588938
Highly Cited
1996
Highly Cited
1996
Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death
E. Morishita
,
S. Masuda
,
M. Nagao
,
Y. Yasuda
,
R. Sasaki
Neuroscience
1996
Corpus ID: 41374229
Review
1995
Review
1995
Nitroimidazoles and imaging hypoxia
A. Nunn
,
K. Linder
,
H. Strauss
European Journal of Nuclear Medicine
1995
Corpus ID: 19759210
Decreased tissue oxygen tension is a component of many diseases. Although hypoxia can be secondary to a low inspired P02 or a…
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Review
1987
Review
1987
Myocardial contractile function during ischemia and hypoxia.
D. Allen
,
C. Orchard
Circulation Research
1987
Corpus ID: 1630073
There is good evidence that elevated [Ca2+]i, produced by an influx of Ca2+ in exchange for Na+, is the underlying pathology in…
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Review
1984
Review
1984
Effect of local hyperthermia on blood flow and microenvironment: a review.
C. Song
Cancer Research
1984
Corpus ID: 19415152
The blood flow in tumors varies considerably among different tumor types. Even in the same tumor, the distribution of vasculature…
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