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Hyperpolarized Carbon C 13 Pyruvate

Known as: Hyperpolarized 13C-Pyruvate, Hyperpolarized Pyruvate (13C) 
A hyperpolarized pyruvate labeled with carbon C 13, with potential usage in the diagnostic imaging of cancer cells. Upon administration, carbon C 13… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
0519992017

Papers overview

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2013
2013
Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI.
The exquisite NMR spectral sensitivity and negligible reactivity of hyperpolarized xenon-129 (HP(129)Xe) make it attractive for a… (More)
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2013
2013
Measuring mitochondrial metabolism in rat brain in vivo using MR Spectroscopy of hyperpolarized [2-¹³C]pyruvate.
Hyperpolarized [1-(13) C]pyruvate ([1-(13) C]Pyr) has been used to assess metabolism in healthy and diseased states, focusing on… (More)
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2013
2013
Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas.
Renal cell carcinomas (RCC) are a heterogeneous group of tumors with a wide range of aggressiveness. Noninvasive methods to… (More)
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2013
2013
Pulmonary ventilation visualized using hyperpolarized helium-3 and xenon-129 magnetic resonance imaging: differences in COPD and relationship to emphysema.
In subjects with chronic obstructive pulmonary disease (COPD), hyperpolarized xenon-129 ((129)Xe) magnetic resonance imaging (MRI… (More)
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2013
2013
Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors.
Hyperpolarized (13)C magnetic resonance spectroscopy provides a unique opportunity to detect real-time metabolic fluxes as a… (More)
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2012
2012
Evaluating bronchodilator effects in chronic obstructive pulmonary disease using diffusion-weighted hyperpolarized helium-3 magnetic resonance imaging.
The objective of this study was to evaluate the regional effects of bronchodilator administration in chronic obstructive… (More)
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2011
2011
Hyperpolarized ³He magnetic resonance imaging: preliminary evaluation of phenotyping potential in chronic obstructive pulmonary disease.
RATIONALE AND OBJECTIVES Emphysema and small airway obstruction are the pathological hallmarks of chronic obstructive pulmonary… (More)
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2009
2009
In Vivo Carbon-13 Dynamic MRS and MRSI of Normal and Fasted Rat Liver with Hyperpolarized 13C-Pyruvate
The use of in vivo 13C nuclear magnetic resonance spectroscopy in probing metabolic pathways to study normal metabolism and… (More)
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2008
2008
Bioenergetic differences selectively sensitize tumorigenic liver progenitor cells to a new gold(I) compound.
A hallmark of cancer cells is their ability to evade apoptosis and mitochondria play a critical role in this process. Delineating… (More)
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1999
1999
Exploring surfaces and cavities in lipoxygenase and other proteins by hyperpolarized xenon-129 NMR.
This paper presents an exploratory study of the binding interactions of xenon with the surface of several different proteins in… (More)
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