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Hyperpolarized Carbon C 13 Pyruvate

Known as: Hyperpolarized 13C-Pyruvate, Hyperpolarized Pyruvate (13C) 
A hyperpolarized pyruvate labeled with carbon C 13, with potential usage in the diagnostic imaging of cancer cells. Upon administration, carbon C 13… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Role of metabolic imaging in diagnosis of primary, metastatic, and recurrent prostate cancer.
PURPOSE OF REVIEW The present review describes the current role of metabolic imaging techniques such as multiparametric MRI… 
2020
2020
In vivo detection of d‐amino acid oxidase with hyperpolarized d‐[1‐13C]alanine
d‐amino acid oxidase (DAO) is a peroxisomal enzyme that catalyzes the oxidative deamination of several neutral and basic d‐amino… 
2018
2018
Hyperpolarized [1-13C] pyruvate MR spectroscopy detect altered glycolysis in the brain of a cognitively impaired mouse model fed high-fat diet
Higher dietary intakes of saturated fatty acid increase the risk of developing Alzheimer’s disease and dementia, and even in… 
2016
2016
Screening CEST contrast agents using ultrafast CEST imaging.
Highly Cited
2014
Highly Cited
2014
Assessment of lung function in asthma and COPD using hyperpolarized 129Xe chemical shift saturation recovery spectroscopy and dissolved‐phase MRI
Magnetic‐resonance spectroscopy and imaging using hyperpolarized xenon‐129 show great potential for evaluation of the most… 
Highly Cited
2013
Highly Cited
2013
Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI
Significance Lung diseases comprise the third leading cause of death in the United States and could benefit from new imaging… 
Highly Cited
2013
Highly Cited
2013
Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors.
Hyperpolarized (13)C magnetic resonance spectroscopy provides a unique opportunity to detect real-time metabolic fluxes as a… 
2013
2013
Hyperpolarized helium‐3 magnetic resonance imaging of chronic obstructive pulmonary disease exacerbation
A chronic obstructive pulmonary disease (COPD) exsmoker underwent pulmonary function tests and hyperpolarized helium‐3 (3He… 
Highly Cited
2009
Highly Cited
2009
In Vivo Carbon-13 Dynamic MRS and MRSI of Normal and Fasted Rat Liver with Hyperpolarized 13C-Pyruvate
BackgroundThe use of in vivo13C nuclear magnetic resonance spectroscopy in probing metabolic pathways to study normal metabolism… 
1999
1999
Exploring surfaces and cavities in lipoxygenase and other proteins by hyperpolarized xenon-129 NMR.
This paper presents an exploratory study of the binding interactions of xenon with the surface of several different proteins in… 
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