Hydrocodone

Known as: 4,5-alpha-Epoxy-3-methoxy-17-methylmorphinan-6-one, Idrocodone, Hydrocodon 
A semisynthetic hydrogenated codeine derivative and opioid agonist with analgesic and antitussive effects. Hydrocodone primarily binds to and… (More)

Topic mentions per year

Topic mentions per year

1945-2018
05019452017

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND The use of prescription opioid medications has increased greatly in the United States during the past two decades; in… (More)
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2010
2010
Fatal opioid toxicity occurred in a developmentally delayed child aged 5 years 9 months who was inadvertently administered high… (More)
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2008
2008
Abuse of prescription opioids has risen precipitously in the United States. Few controlled comparisons of the abuse liability of… (More)
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2006
2006
Concern about abuse/dependence in chronic pain patients taking opioid analgesics may lead to undertreatment of pain, yet little… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT During a clinical trial of a novel hydrocodone/acetaminophen combination, a high incidence of serum alanine… (More)
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2005
2005
BACKGROUND Multiple studies have documented the incidence of illicit drug use and abuse of opioids. Over the years, several… (More)
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2004
2004
BACKGROUND Current British Thoracic Society guidelines do not recommend routinely the combined use of a benzodiazepine and opiate… (More)
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2004
2004
AIM To determine the Michaelis-Menten kinetics of hydrocodone metabolism to its O- and N-demethylated products, hydromorphone and… (More)
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1997
1997
Enzymatic conversion of hydrocodone to hydromorphone is catalyzed by cytochrome P450 2D6, which is inactive in about 7% of… (More)
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1993
1993
The contribution of cytochrome P450 2D6 (CYP2D6) to the formation of hydrocodone's active metabolite, hydromorphone, was examined… (More)
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