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Homocitrate synthase

Known as: 3-hydroxybutane-1,2,4-tricarboxylate 2-oxoglutarate-lyase (CoA-acetylating) 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Oxo-Acid-Lyases

Papers overview

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2016
2016
Characterization of recombinant homocitrate synthase from Candida albicans.
2011
2011
Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase.
2010
2010
Structural Basis for l-Lysine Feedback Inhibition of Homocitrate Synthase*♦
The α-aminoadipate pathway of lysine biosynthesis is modulated at the transcriptional and biochemical levels by feedback… 
2009
2009
Mechanism of Substrate Recognition and Insight into Feedback Inhibition of Homocitrate Synthase from Thermus thermophilus*
Homocitrate synthase (HCS) catalyzes aldol-type condensation of acetyl coenzyme A (acetyl-CoA) and α-ketoglutarate (α-KG) to… 
2005
2005
Regulatory Mechanism of Histidine-tagged Homocitrate Synthase from Saccharomyces cerevisiae
Homocitrate synthase (HCS) catalyzes one of the regulated steps of the α-aminoadipate pathway for lysine biosynthesis in fungi… 
2005
2005
Leader Peptide-mediated Transcriptional Attenuation of Lysine Biosynthetic Gene Cluster in Thermus thermophilus*
The molecular mechanism for regulation of the genes involved in the biosynthesis of amino acids is poorly identified in Thermus… 
2004
2004
Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
Kinetic data have been collected suggesting a preferred sequential ordered kinetic mechanism for the histidine-tagged homocitrate… 
2004
2004
General and specific controls of lysine biosynthesis in Saccharomyces cerevisiae
SummarySix of the eight enzymes of the α-aninoadipate pathway for the biosynthesis of lysine in Saccharomyces cerevisiae were… 
2002
2002
Characterization of bacterial homocitrate synthase involved in lysine biosynthesis
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