Histone H3 Dimethyl Lys27
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H3K27me3 is deposited at promoters by the preferential association of Polycomb repressive complex 2 (PRC2) with CpG-rich DNA… Expand Recent studies have identified a Lys 27-to-methionine (K27M) mutation at one allele of H3F3A, one of the two genes encoding… Expand Trimethylation of histone H3 on lysine 27 (H3K27me3) is a repressive posttranslational modification mediated by the histone… Expand While reversible histone modifications are linked to an ever-expanding range of biological functions, the demethylases for… Expand Combinatorial readout of multiple covalent histone modifications is poorly understood. We provide insights into how an activating… Expand The genomes of higher organisms are packaged in nucleosomes with functional histone modifications. Until now, genome-wide… Expand Core RNA-processing reactions in eukaryotic cells occur cotranscriptionally in a chromatin context, but the relationship between… Expand ABSTRACT The mammalian Polycomblike protein PHF1 was previously shown to interact with the Polycomb group (PcG) protein Ezh2, a… Expand The plant Polycomb‐group (Pc‐G) protein CURLY LEAF (CLF) is required to repress targets such as AGAMOUS (AG) and… Expand Vernalization is the acceleration of flowering by prolonged cold that aligns the onset of reproductive development with spring… Expand