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Hereditary Malignant Neoplasm
Known as:
Familial Cancer
, Familial Malignant Neoplasm
, Hereditary Cancer
Cancer that occurs in families more often than would be expected by chance. These cancers often occur at an early age, and may indicate the presence…
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National Institutes of Health
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Related topics
Related topics
2 relations
Neoplastic Cell
cancer cell
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Metformin: a diabetes drug for cancer, or a cancer drug for diabetics?
Matthew Martin
,
R. Marais
Journal of Clinical Oncology
2012
Corpus ID: 38278889
Clinical evidence that diabetics receiving metformin have a reduced lifetime incidence of cancer has sparked keen interest in the…
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Review
2009
Review
2009
Cancer genetic risk assessment and referral patterns in primary care.
H. Vig
,
J. Armstrong
,
+5 authors
N. Meropol
Genetic Testing and Molecular Biomarkers
2009
Corpus ID: 5113520
PURPOSE This study was undertaken to describe cancer risk assessment practices among primary care providers (PCPs). METHODS An…
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Highly Cited
2008
Highly Cited
2008
Epigenetic signatures of familial cancer are characteristic of tumor type and family category.
Emmi I. Joensuu
,
W. Abdel-Rahman
,
M. Ollikainen
,
Salla Ruosaari
,
S. Knuutila
,
P. Peltomäki
Cancer Research
2008
Corpus ID: 1800662
Tumor suppressor genes (TSG) may be inactivated by methylation of critical CpG sites in their promoter regions, providing targets…
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Highly Cited
2001
Highly Cited
2001
Familial bladder cancer in the National Swedish Family Cancer Database.
K. Plná
,
K. Hemminki
Journal of Urology
2001
Corpus ID: 44601483
Review
1999
Review
1999
Transcription elongation and human disease.
J. Conaway
,
R. Conaway
Annual Review of Biochemistry
1999
Corpus ID: 30167944
Eukaryotic mRNA synthesis is catalyzed by multisubunit RNA polymerase II and proceeds through multiple stages referred to as…
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Highly Cited
1998
Highly Cited
1998
Age‐specific familial risks in common cancers of the offspring
K. Hemminki
,
P. Vaittinen
,
P. Kyyrönen
International Journal of Cancer
1998
Corpus ID: 28671653
Quantitative data on familial cancer risks are important for clinical, psychological and scientific reasons. The available…
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Highly Cited
1993
Highly Cited
1993
Confirmation of chromosome 9p linkage in familial melanoma.
D. Nancarrow
,
G. Mann
,
+7 authors
J. Weber
American Journal of Human Genetics
1993
Corpus ID: 34517506
Malignant melanoma occurs as a familial cancer in 5%-10% of cases where it segregates in a manner consistent with autosomal…
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Highly Cited
1985
Highly Cited
1985
Chromosomal radiosensitivity during the G2 cell-cycle period of skin fibroblasts from individuals with familial cancer.
R. Parshad
,
K. Sanford
,
G. Jones
Proceedings of the National Academy of Sciences…
1985
Corpus ID: 1607656
We reported previously that human cells after neoplastic transformation in culture had acquired an increased susceptibility to…
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1983
1983
Model hereditary cancers of man.
A. Knudson
Progress in Nucleic Acid Research and Molecular…
1983
Corpus ID: 39607247
Highly Cited
1980
Highly Cited
1980
Familial atypical multiple mole melanoma (FAMMM) syndrome: genetic heterogeneity and malignant melanoma.
H. T. Lynch
,
R. Fusaro
,
J. Pester
,
J. Lynch
British Journal of Cancer
1980
Corpus ID: 6818117
Clinical-pathologic-genetic studies were performed on 3 kindreds showing the familial atypical multiple mole-melanoma syndrome…
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