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Hereditary Malignant Neoplasm

Known as: Familial Cancer, Familial Malignant Neoplasm, Hereditary Cancer 
Cancer that occurs in families more often than would be expected by chance. These cancers often occur at an early age, and may indicate the presence… 
National Institutes of Health

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Neoplastic Cellcancer cell

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers
Objective To investigate the potential contribution of germline sequence alterations in the BAP1 gene in uveal melanoma (UM… 
Highly Cited
2005
Highly Cited
2005
The general public's information needs and perceptions regarding hereditary cancer: an application of the Integrated Change Model.
Review
2005
Review
2005
Psychological Impact of Genetic Counseling for Familial Cancer: A Systematic Review and Meta-Analysis
Background: Identification of a genetic basis underlying certain types of cancer has led to an increase in demand for genetic… 
Highly Cited
2001
Highly Cited
2001
von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.
von Hippel-Lindau (VHL) disease is a hereditary cancer syndrome caused by germ line mutation of the von Hippel-Lindau tumor… 
Highly Cited
1998
Highly Cited
1998
Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk.
PURPOSE Previous studies of mutations in BRCA1 or BRCA2 have used detection methods that may underestimate the actual frequency… 
Review
1997
Review
1997
Human cancer syndromes: clues to the origin and nature of cancer.
More than 20 different hereditary cancer syndromes have now been defined and attributed to specific germline mutations in various… 
Highly Cited
1997
Highly Cited
1997
The use and interpretation of commercial APC gene testing for familial adenomatous polyposis.
BACKGROUND The use of commercially available tests for genes linked to familial cancer has aroused concern about the impact of… 
Highly Cited
1996
Highly Cited
1996
Phenotypic expression in von Hippel-Lindau disease: correlations with germline VHL gene mutations.
Von Hippel-Lindau disease is an autosomal dominantly inherited familial cancer syndrome predisposing to retinal and central… 
Review
1995
Review
1995
Cell-cycle regulators and cancer.
Review
1980
Review
1980
Familial carotid body tumors: Case report and epidemiologic review
We report on the cases of two sisters with carotid body tumor (CBT) and present a literature review that assembles epidemiologic… 
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