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Hereditary Malignant Neoplasm

Known as: Familial Cancer, Familial Malignant Neoplasm, Hereditary Cancer 
Cancer that occurs in families more often than would be expected by chance. These cancers often occur at an early age, and may indicate the presence… 
National Institutes of Health

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Neoplastic Cellcancer cell

Papers overview

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Highly Cited
2012
Highly Cited
2012
Metformin: a diabetes drug for cancer, or a cancer drug for diabetics?
Clinical evidence that diabetics receiving metformin have a reduced lifetime incidence of cancer has sparked keen interest in the… 
Review
2009
Review
2009
Cancer genetic risk assessment and referral patterns in primary care.
PURPOSE This study was undertaken to describe cancer risk assessment practices among primary care providers (PCPs). METHODS An… 
Highly Cited
2008
Highly Cited
2008
Epigenetic signatures of familial cancer are characteristic of tumor type and family category.
Tumor suppressor genes (TSG) may be inactivated by methylation of critical CpG sites in their promoter regions, providing targets… 
Highly Cited
2001
Highly Cited
2001
Familial bladder cancer in the National Swedish Family Cancer Database.
Review
1999
Review
1999
Transcription elongation and human disease.
Eukaryotic mRNA synthesis is catalyzed by multisubunit RNA polymerase II and proceeds through multiple stages referred to as… 
Highly Cited
1998
Highly Cited
1998
Age‐specific familial risks in common cancers of the offspring
Quantitative data on familial cancer risks are important for clinical, psychological and scientific reasons. The available… 
Highly Cited
1993
Highly Cited
1993
Confirmation of chromosome 9p linkage in familial melanoma.
Malignant melanoma occurs as a familial cancer in 5%-10% of cases where it segregates in a manner consistent with autosomal… 
Highly Cited
1985
Highly Cited
1985
Chromosomal radiosensitivity during the G2 cell-cycle period of skin fibroblasts from individuals with familial cancer.
We reported previously that human cells after neoplastic transformation in culture had acquired an increased susceptibility to… 
1983
1983
Model hereditary cancers of man.
Highly Cited
1980
Highly Cited
1980
Familial atypical multiple mole melanoma (FAMMM) syndrome: genetic heterogeneity and malignant melanoma.
Clinical-pathologic-genetic studies were performed on 3 kindreds showing the familial atypical multiple mole-melanoma syndrome… 
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